Glaich Adrienne S, Behroozan Daniel S, Cohen Joel L, Goldberg Leonard H
DermSurgery Associates, Houston, TX 77030, USA.
Dermatol Surg. 2006 Feb;32(2):316-9. doi: 10.1111/j.1524-4725.2006.32059.x.
Lymphoepithelioma-like carcinoma of the skin (LELCS) is a rare cutaneous neoplasm with microscopic similarities to non-cutaneous lymphoepitheliomatous malignancies, particularly undifferentiated carcinoma of the nasopharynx. It can be clinically and histologically confused with other benign and malignant tumors. If not adequately treated, recurrence and distant metastasis are probable. We present two cases of LELCS treated surgically with complete microscopic margin control (one by the Mohs method and the other with en face permanent sections) and review the literature.
皮肤淋巴上皮瘤样癌(LELCS)是一种罕见的皮肤肿瘤,在显微镜下与非皮肤淋巴上皮瘤恶性肿瘤相似,尤其是鼻咽癌未分化癌。它在临床和组织学上可能与其他良性和恶性肿瘤混淆。如果治疗不充分,可能会复发和远处转移。我们报告两例通过手术治疗且显微镜下切缘完全控制的LELCS病例(一例采用莫氏手术方法,另一例采用整块永久切片法)并复习相关文献。