Stang Paul E, Brandenburg Nancy A, Lane Michael C, Merikangas Kathleen R, Von Korff Michael R, Kessler Ronald C
Department of Health, West Chester University and Galt Associates West Chester, PA, USA.
Psychosom Med. 2006 Jan-Feb;68(1):152-8. doi: 10.1097/01.psy.0000195821.25811.b4.
To estimate the prevalence of comorbidity among people with arthritis in the US adult population and to determine the role of comorbidity in accounting for the association of arthritis with days out of role (a measure of inability to work or carry out normal activities).
Data come from the National Comorbidity Survey Replication (NCS-R), a nationally representative household survey of 9,282 respondents ages 18 and older carried out in 2001 to 2003. Arthritis was assessed by self-report in a chronic-conditions checklist, along with a wide range of other physical conditions. Mental and substance use disorders were ascertained with the World Health Organization Composite International Diagnostic Interview (CIDI). Number of days out of role was assessed for the 30 days before the interview.
Arthritis was reported by 27.3% of respondents, 80.9% of whom also reported at least one other physical or mental disorder, including 45.6% with another chronic pain condition, 62.3% with another chronic physical condition, and 24.3% with a 12-month mental disorder. Arthritis was significantly associated with days out of role, but comorbidity explained more than half of this association. No significant interactions were found between arthritis and the other conditions in predicting days out of role.
Comorbidity is the rule rather than the exception among people with arthritis. Comorbidity accounts for most of the days out of role associated with arthritis. The societal burden of arthritis needs to be understood and managed within the context of these comorbid conditions.
评估美国成年人群中关节炎患者的共病患病率,并确定共病在解释关节炎与失能天数(衡量无法工作或进行正常活动的指标)之间关联中所起的作用。
数据来自全国共病调查复制研究(NCS-R),这是一项于2001年至2003年对9282名18岁及以上受访者进行的具有全国代表性的家庭调查。通过慢性疾病清单中的自我报告评估关节炎,同时评估一系列其他身体状况。使用世界卫生组织综合国际诊断访谈(CIDI)确定精神和物质使用障碍。在访谈前30天评估失能天数。
27.3%的受访者报告患有关节炎,其中80.9%的人还报告至少患有另一种身体或精神疾病,包括45.6%患有另一种慢性疼痛疾病,62.3%患有另一种慢性身体疾病,24.3%患有12个月内的精神疾病。关节炎与失能天数显著相关,但共病解释了这种关联的一半以上。在预测失能天数方面,未发现关节炎与其他疾病之间存在显著相互作用。
共病在关节炎患者中是常态而非例外。共病是与关节炎相关的失能天数的主要原因。需要在这些共病状况的背景下理解和管理关节炎的社会负担。