Braun Gerald S, Horster Sophia, Wagner Katrin S, Ihrler Stephan, Schmid Holger
Division of Nephrology and Immunology, RWTH University, Aachen, Germany.
Postgrad Med J. 2007 Feb;83(976):87-94. doi: 10.1136/pgmj.2006.046078.
Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia. This review summarises the classification and clinical and therapeutic aspects of cryoglobulinaemic vasculitis and glomerulonephritis.
冷球蛋白血症可导致皮肤血管炎和肾小球肾炎,有可能导致终末期肾衰竭。相当一部分冷球蛋白血症继发于丙型肝炎病毒感染。新出现的抗病毒治疗方案为这些冷球蛋白血症病例的病因治疗提供了机会。本综述总结了冷球蛋白血症性血管炎和肾小球肾炎的分类、临床及治疗方面。