大型中心老年肥胖症患者的治疗结果。
Outcomes among elderly bariatric patients at a high-volume center.
作者信息
Dunkle-Blatter Stephanie E, St Jean Michael R, Whitehead Carly, Strodel William, Bennotti Peter N, Still Christopher, Reed Mary Jane, Wood Craig G, Petrick Anthony T
机构信息
Geisinger Medical Center, Danville, Pennsylvania 17822-2170, USA.
出版信息
Surg Obes Relat Dis. 2007 Mar-Apr;3(2):163-9; discussion 169-70. doi: 10.1016/j.soard.2006.12.004. Epub 2007 Feb 27.
BACKGROUND
Bariatric surgery in elderly patients remains controversial. With a growing morbidly obese elderly population, management strategies and treatment outcomes need to be evaluated.
METHODS
We reviewed all bariatric cases from 2001 to 2005 at a single institution. The preoperative factors (body mass index, smoking status, co-morbid conditions, number of medications) and surgical information (operation and length of stay) were recorded. Patients >60 years old who had undergone Roux-en-Y gastric bypass (RYGB) were followed up, and their surgical outcomes were analyzed (reduction in medications, resolution of diabetes mellitus and hypertension, percentage of excess body weight loss, complications, and mortality).
RESULTS
Of 1065 patients, 76 (7.1%) were aged > or =60 years. Of these 76 patients, 61 (5.7%) underwent RYGB. The other 989 patients (92.9%) were <60 years old, and 952 of these underwent RYGB. In the older group, the mean number of co-morbid conditions was 10 +/- 3.3, 70.5% had diabetes, and 83.6% had hypertension. In the younger group, the mean number of co-morbidities was 4.7 +/- 2.3. The mean number of preoperative medications was 10 +/- 4.5 in the older group compared with 6.0 +/- 4.3 in the younger group. The mean length of stay was 2.9 days in both groups. Postoperatively, medications were reduced by nearly 50% in both groups. Diabetes and hypertension resolved or improved significantly in both groups. The mean percentage of excess body weight loss was lower in the older patients (54.9% versus 60.1%; P = .09). The 90-day operative mortality rate was 1.64% in the older group versus 0.53% for the younger group (P = NS).
CONCLUSION
Our data support the use of RYGB in older patients in programs prepared to comprehensively manage the medical co-morbidities. Although the percentage of excess body weight loss was less, the mortality was acceptable despite the greater number of co-morbidities. Both diabetes and hypertension were more common in this population, with trends toward better improvement after RYGB than in younger patients.
背景
老年患者的减肥手术仍存在争议。随着病态肥胖老年人口的增加,需要评估管理策略和治疗效果。
方法
我们回顾了某单一机构2001年至2005年期间所有的减肥手术病例。记录术前因素(体重指数、吸烟状况、合并疾病、用药数量)和手术信息(手术方式和住院时间)。对年龄大于60岁且接受了Roux-en-Y胃旁路术(RYGB)的患者进行随访,并分析其手术结果(用药减少情况、糖尿病和高血压的缓解情况、超重体重减轻百分比、并发症和死亡率)。
结果
在1065例患者中,76例(7.1%)年龄大于或等于60岁。在这76例患者中,61例(5.7%)接受了RYGB。其他989例患者(92.9%)年龄小于60岁,其中952例接受了RYGB。在老年组中,合并疾病的平均数量为10±3.3,70.5%患有糖尿病,83.6%患有高血压。在年轻组中,合并疾病的平均数量为4.7±2.3。老年组术前用药的平均数量为10±4.5,而年轻组为6.0±4.3。两组的平均住院时间均为2.9天。术后,两组的用药量均减少了近50%。两组的糖尿病和高血压均得到明显缓解或改善。老年患者超重体重减轻的平均百分比更低(54.9%对60.1%;P = 0.09)。老年组90天手术死亡率为1.64%,而年轻组为0.53%(P = 无显著差异)。
结论
我们的数据支持在有能力全面管理合并疾病的项目中,对老年患者使用RYGB。尽管超重体重减轻的百分比较低,但尽管合并疾病较多,死亡率仍可接受。糖尿病和高血压在该人群中更为常见,RYGB术后改善的趋势比年轻患者更好。