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压力管理:细胞如何控制其转座子。

Stress management: how cells take control of their transposons.

作者信息

Ebina Hirotaka, Levin Henry L

机构信息

Section on Eukaryotic Transposable Elements, Laboratory of Gene Regulation and Development, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

Section on Eukaryotic Transposable Elements, Laboratory of Gene Regulation and Development, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

出版信息

Mol Cell. 2007 Jul 20;27(2):180-181. doi: 10.1016/j.molcel.2007.07.004.

Abstract

In this issue of Molecular Cell, Dai et al. (2007) describe their exciting discovery that, in Saccharomyces cerevisiae, the integrase of retrotransposon Ty5 is phosphorylated, and this modification stabilizes the interaction between integrase and Sir4p that directs integration to heterochromatin.

摘要

在本期《分子细胞》杂志中,戴等人(2007年)描述了他们令人兴奋的发现:在酿酒酵母中,逆转座子Ty5的整合酶被磷酸化,这种修饰稳定了整合酶与Sir4p之间的相互作用,从而将整合导向异染色质。

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