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Red blood cell insulin receptors in health and disease.

作者信息

Gambhir K K, Agarwal V R

机构信息

Department of Medicine, College of Medicine, Howard University, Washington, DC 20059.

出版信息

Biochem Med Metab Biol. 1991 Apr;45(2):133-53. doi: 10.1016/0885-4505(91)90015-d.

Abstract

Structure and characteristics of erythrocyte insulin receptor. Red blood cell age and insulin receptors. Insulin receptors in human disease states. Obesity. Chronic renal failure. Acanthosis nigricans. Miscellaneous disease states. Insulin receptors in children. Insulin receptors in women during pregnancy. Insulin binding and other hormones. Comparison of biosynthetic insulin, pancreatic human insulin and porcine insulin binding to erythrocytes. Effect of exercise on insulin binding to red blood cells of normal human volunteers. Miscellaneous insulin binding studies. Insulin internalization and degradation. Insulin and erythrocyte metabolism. Summary and conclusion.

摘要

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