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颈椎手术后谵妄的发生率及危险因素。

Incidence and risk factors of postoperative delirium in cervical spine surgery.

机构信息

Department of Orthopaedic Surgery, Kochi Medical School, Kochi, Japan.

出版信息

Spine (Phila Pa 1976). 2009 Nov 1;34(23):2500-4. doi: 10.1097/BRS.0b013e3181b321e6.

Abstract

STUDY DESIGN

Retrospective clinical review and prospective report of postoperative delirium after cervical spine surgeries.

OBJECTIVE

To investigate factors contributing to the development of delirium after cervical surgery and see whether amended therapeutic protocols could improve or alter postoperative outcomes.

SUMMARY OF BACKGROUND DATA

Important consequences of postoperative delirium for the orthopedic patients include impaired recovery and increased morbidity and mortality. Although its risk factors have been reported in orthopedic surgery, there are a very few reports regarding postoperative delirium in spine surgery.

METHODS

Eighty-one cervical myelopathy patients were retrospectively examined about the incidence of postoperative delirium and the risk factors. Similarly, 41 patients who received postoperative care under modified protocols were prospectively examined.

RESULTS

Postoperative delirium occurred more commonly in patients over 70 years and those with hearing impairment. Patients who received high-dose methylprednisolone (>1000 mg) demonstrated an increased incidence of postoperative delirium. Under modified protocol, we reduced the usage of methylprednisolone and encouraged free body movement with cervical orthosis immediately after surgery. The incidence of postoperative delirium was significantly lower under the modified protocol.

CONCLUSION

Early commencement of mobilization after cervical spine surgery would be crucial to the prevention of postoperative delirium in the elderly.

摘要

研究设计

颈椎手术后谵妄的回顾性临床研究和术后报告。

目的

探讨颈椎手术后发生谵妄的相关因素,以及修正后的治疗方案是否可以改善或改变术后结果。

背景资料总结

术后谵妄对骨科患者的重要影响包括恢复受损和发病率及死亡率增加。尽管已经有关于骨科手术后发生谵妄的危险因素的报道,但关于脊柱手术后发生术后谵妄的报道却很少。

方法

对 81 例颈椎脊髓病患者进行回顾性检查,以了解术后谵妄的发生率和危险因素。同样,对 41 例接受改良方案术后护理的患者进行前瞻性检查。

结果

70 岁以上和听力受损的患者更常发生术后谵妄。接受大剂量甲基强的松龙(>1000mg)治疗的患者术后谵妄发生率增加。在改良方案下,我们减少了甲基强的松龙的使用,并鼓励术后立即在颈椎支具的保护下自由活动。改良方案下术后谵妄的发生率明显降低。

结论

颈椎手术后尽早开始活动对于预防老年患者术后谵妄至关重要。

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