Cancer Survivor Center for Health and Wellbeing, Aspen, CO, USA.
Phys Sportsmed. 2009 Oct;37(3):68-77. doi: 10.3810/psm.2009.10.1731.
Changes in aerobic capacity were evaluated after 12 weeks of training among a motivated heterogeneous group of cancer survivors (N = 54 [41 women and 13 men]), living at moderate altitude. Changes in power at lactate threshold (PT(lact)), peak power (P(peak)), and peak oxygen uptake (VO(2) peak) were evaluated in this group (average age, 53.8 + or - 10.8 years) that completed a minimum of 12 weeks of an individualized exercise program (on average 5 days x week(-1) for 47.5 + or - 17.2 min x session(-1)). Daily exercise duration was based on the goals and functional capacity of each individual. Training intensity for each subject was based on heart rate (HR) value at lactate threshold (T(lact)) obtained during a symptom-limited cardiopulmonary exercise test. Intensity was categorized into 5 ranges: recovery (60%-80% HR T(lact)); endurance (80%-100% HR T(lact)); threshold (100%-105% HR T(lact)); intervals (105%-115% HR T(lact)); and maximal efforts (> or = 115% HR T(lact)). Overall compliance with the exercise prescription was approximately 72% and subjects reported exercising within the 5 training ranges, 12.1%, 63.9%, 18.6%, 4.2%, and 1.2% of the time, respectively. After training, PT(lact) increased 9.5% (121.8 + or - 43.5 vs 133.2 + or - 34.1 W; P < 0.05), P(peak) increased 12.6% (175.5 + or - 55.6 vs 195.6 + or - 54.2 W; P < 0.05) and VO(2) peak increased 11.4% (33.4 + or - 12.5 vs 37.2 + or - 10.4 mL x kg(-1) x min(-1); P < 0.05). The results of this research indicate that: 1) cardiopulmonary exercise testing with lactate threshold determination was safe and effective in the evaluation and exercise prescription phase for a group of cancer survivors and 2) a training program based on 2 higher intensity workouts per week can elicit significant changes in aerobic capacity of a diverse group of cancer survivors.
在经过 12 周的训练后，评估了生活在中等海拔地区的、由癌症幸存者组成的（N=54[41 名女性和 13 名男性]）、积极性较高的异质群体的有氧能力变化。在这一群体（平均年龄为 53.8+/-10.8 岁）中评估了乳酸阈（PT(lact)）、峰值功率（P(peak)）和峰值摄氧量（VO(2)peak）的变化，他们完成了至少 12 周的个性化运动计划（平均每周 5 天，每次运动 47.5+/-17.2 分钟）。每个个体的日常运动时间基于目标和功能能力。每位受试者的训练强度基于乳酸阈（T(lact)）时的心率（HR）值，在一项症状限制心肺运动测试中获得。强度分为 5 个范围：恢复（60%-80% HR T(lact)）；耐力（80%-100% HR T(lact)）；阈（100%-105% HR T(lact)）；间隔（105%-115% HR T(lact)）和最大努力（>或= 115% HR T(lact)）。运动处方的总体依从率约为 72%，并且受试者报告在 5 个训练范围内分别进行运动，时间分别为 12.1%、63.9%、18.6%、4.2%和 1.2%。训练后，PT(lact)增加了 9.5%（121.8+/-43.5 与 133.2+/-34.1 W；P<0.05），P(peak)增加了 12.6%（175.5+/-55.6 与 195.6+/-54.2 W；P<0.05），VO(2)peak 增加了 11.4%（33.4+/-12.5 与 37.2+/-10.4 mL x kg(-1) x min(-1)；P<0.05）。这项研究的结果表明：1）乳酸阈测定的心肺运动测试在评估和运动处方阶段对一组癌症幸存者是安全有效的；2）每周进行 2 次高强度训练的训练计划可以引起多样化癌症幸存者有氧能力的显著变化。
