类风湿关节炎患者颈椎破坏性病变枕颈融合术的手术并发症及处理

Surgical complications and management of occipitothoracic fusion for cervical destructive lesions in RA patients.

作者信息

Hirano Kenichi, Matsuyama Yukihiro, Sakai Yoshihito, Katayama Yoshito, Imagama Shiro, Ito Zenya, Wakao Norimitsu, Yoshihara Hisatake, Miura Yasushi, Kamiya Mitsuhiro, Sato Koji, Nakamura Hiroshi, Ishiguro Naoki

机构信息

Department of Orthopaedic Surgery, Toyohashi Municipal Hospital, Toyohashi, Japan.

出版信息

J Spinal Disord Tech. 2010 Apr;23(2):121-6. doi: 10.1097/BSD.0b013e3181993315.

Abstract

STUDY DESIGN

Retrospective clinical study.

OBJECTIVE

The objective of this study is to evaluate the clinical outcome of occipitothoracic fusion for severe destructive cervical lesions in rheumatoid arthritis (RA) patients with myelopathy and/or occipitocervical pain, and to discuss surgical complications. The complication rates are compared between 2 groups treated with different instrumentation techniques.

SUMMARY OF BACKGROUND DATA

Few studies have reported on the results of occipitothoracic fusion in RA patients.

METHODS

In this study, 56 RA patients with myelopathy and/or occipitocervical pain caused by destructive cervical lesions were studied. The patients were divided into 2 groups A and B, according to the used rod diameter and the application of the cervical pedicle screw system. Group A included 38 patients treated with Unit rods (4.75 mm). Group B included 18 patients treated with cervical pedicle screw system (3.2 mm or 3.5 mm diameter rod). Clinical results and surgical complications were evaluated.

RESULTS

Mean follow-up time was 36.2 months. Fifteen patients died during follow-up at the mean age of 67.3 years. None died from their cervical lesions. The neurologic status in 46 patients (82%) had improved at least 1 class in the modified Ranawat scale. Perioperative complications occurred in 16 (28.6%), thoracic spine lesions in 11 (19.6%), implant failure in 13 (23.2%), and surgical site infection in 8 (14.3%). There was a tendency for more fractures and pedicle screw pullouts at the lowest level of the fusion area to occur in group B. The neurologic improvement of patients undergoing occipitothoracic fusion after becoming unable to sit owing to their neurologic deficit was poor.

CONCLUSIONS

The current study suggests that occipitothoracic fusion for rheumatoid destructive cervical lesions can be effective in improving neurologic deficit if performed while patients can still sit. Improvements to methodology of this surgery can be made.

摘要

研究设计

回顾性临床研究。

目的

本研究的目的是评估类风湿关节炎(RA)合并脊髓病和/或枕颈疼痛患者严重颈椎破坏性病变行枕颈融合术的临床疗效,并探讨手术并发症。比较采用不同内固定技术治疗的两组患者的并发症发生率。

背景资料总结

很少有研究报道RA患者枕颈融合术的结果。

方法

本研究纳入了56例因颈椎破坏性病变导致脊髓病和/或枕颈疼痛的RA患者。根据所用棒的直径和颈椎椎弓根螺钉系统的应用情况,将患者分为A、B两组。A组38例患者采用单位棒(4.75mm)治疗。B组18例患者采用颈椎椎弓根螺钉系统(直径3.2mm或3.5mm的棒)治疗。评估临床结果和手术并发症。

结果

平均随访时间为36.2个月。15例患者在随访期间死亡,平均年龄67.3岁。均非死于颈椎病变。46例患者(82%)的神经功能状态在改良Ranawat量表中至少改善了1级。围手术期并发症发生16例(28.6%),胸椎病变11例(19.6%),内固定失败13例(23.2%),手术部位感染8例(14.3%)。B组在融合区域最低水平处发生更多骨折和椎弓根螺钉拔出的趋势。因神经功能缺损而无法坐立的患者行枕颈融合术后神经功能改善较差。结论:目前的研究表明,类风湿性颈椎破坏性病变行枕颈融合术,如果在患者仍能坐立时进行,可有效改善神经功能缺损。该手术方法可进行改进。

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