The Fred Hollows Foundation New Zealand, Auckland, New Zealand.
Ophthalmology. 2010 Dec;117(12):2308-14. doi: 10.1016/j.ophtha.2010.03.041. Epub 2010 Jul 3.
To determine the independent, relative, and combined impact of reduced distance and near vision on the vision-specific quality of life (VS QOL) of adults in Timor-Leste.
A population-based cross-sectional eye health survey was conducted in urban and rural areas in Timor-Leste.
Participants were 40 years or older. Those with better eye presenting distance vision worse than 6/18, and every third participant with 6/18 or better vision, completed the VS QOL questionnaire: in total 704 of the 1414 participants.
Distance and near visual acuities were measured and eye health was assessed. The VS QOL questionnaire administered by interview was analyzed using Rasch analysis, univariate analysis, and linear regression to determine associations between VS QOL, demographic factors, and levels of visual impairment.
The Timor-Leste VS QOL questionnaire results.
Rasch analysis confirmed that for participants both with and without visual impairment, the Timor-Leste VS QOL questionnaire provided a valid and reliable measure, was unidimensional, and had appropriate response categories. There was a consistent pattern of deterioration in VS QOL as vision worsened: for each category of distance- and near-vision impairment, there was an independent and significant change in Timor-Leste VS QOL scores between no visual impairment and either mild, moderate, or severe impairment (P < 0.05). Combined distance- and near-vision impairment was associated with a greater impact on VS QOL than categories separately, the impact of severe distance- and near-vision impairment being the greatest and clinically significant: -3.05 (95% confidence interval [CI], -3.60 to -2.49; P<0.05; and 95% CI, <-1.0). Distance vision (37.2%) contributed relatively more than near vision (4.7%) to the total variance in VS QOL (41.9%). Older people, those not married, not literate, and rural dwellers had significantly worse Timor-Leste VS QOL scores (P < 0.05).
This study provides evidence of independent dose-response relationships between distance- and near-vision impairment and poorer VS QOL. Distance-vision impairment had a relatively larger impact on VS QOL than near-vision impairment. Combined distance- and near-vision impairment was associated with a greater impact on VS QOL compared with the independent impact of distance- or near-vision impairment at similar levels.
确定距离和近距视力降低对东帝汶成年人视觉特定生活质量(VS QOL)的独立、相对和综合影响。
在东帝汶的城市和农村地区进行了一项基于人群的横断面眼健康调查。
参与者年龄在 40 岁或以上。那些远距视力较差(低于 6/18)而近距视力较好的人,以及每三分之一视力为 6/18 或更好的人,完成了 VS QOL 问卷:共有 1414 名参与者中的 704 名。
测量远距和近距视力,并评估眼部健康。通过访谈进行的 VS QOL 问卷使用 Rasch 分析、单变量分析和线性回归进行分析,以确定 VS QOL、人口统计学因素和视力损害程度之间的关联。
东帝汶 VS QOL 问卷结果。
Rasch 分析证实,对于有和没有视力障碍的参与者,东帝汶 VS QOL 问卷提供了有效和可靠的测量,是一维的,并且具有适当的反应类别。随着视力的恶化,VS QOL 呈现出一致的恶化模式:对于每一种距离和近距视力损害类别,在没有视力障碍和轻度、中度或重度损害之间,东帝汶 VS QOL 评分都有独立和显著的变化(P < 0.05)。远距和近距视力联合损害对 VS QOL 的影响大于单独损害,严重远距和近距视力损害的影响最大且具有临床意义:-3.05(95%置信区间[CI],-3.60 至-2.49;P<0.05;95%CI,<-1.0)。远距视力(37.2%)对 VS QOL 的总方差的贡献相对大于近距视力(4.7%)(P < 0.05)。年龄较大、未婚、不识字和农村居民的东帝汶 VS QOL 评分明显较差(P < 0.05)。
本研究提供了距离和近距视力损害与较差 VS QOL 之间独立剂量反应关系的证据。远距视力损害对 VS QOL 的影响大于近距视力损害。与相似水平的独立距离或近距视力损害相比,远距和近距视力联合损害与 VS QOL 的更大影响相关。