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原发性肝类癌肿瘤的手术治疗:病例报告

Surgical Control of a Primary Hepatic Carcinoid Tumor: A Case Report.

作者信息

Yokoigawa Norio, Kitade Hiroaki, Ohishi Masaharu, Ozaki Takashi, Miyaso Takeshi, Okazaki Satoshi, Nakai Koji, Yoshida Ryo, Imada Seiki, Imamura Atsushi, Kawaguchi Yusai, Takada Hideho, Shikata Nobuaki, Seki Toshihito, Kwon A-H

机构信息

Departments of Surgery, Kansai Medical University, Osaka, Japan.

出版信息

Case Rep Gastroenterol. 2009 Apr 7;3(1):30-35. doi: 10.1159/000208375.

Abstract

We report a primary hepatic carcinoid tumor occurring in a 47-year-old man. The patient consulted our hospital complaining of epigastralgia. Abdominal ultrasonography, computed tomography scanning, and magnetic resonance imaging showed a large mass in the right lobe of the liver. FDG-PET revealed 18F-FDG uptake by the right hepatic lobe. The tumor was a solid mass with cystic components, approximately 15 cm in diameter. We conducted an extended right lobectomy of the liver. The resected specimen was a solid tumor with cystic components and hemorrhagic lesion. Microscopic findings showed that the tumor cells had round nuclei and formed trabecular patterns. Immunohistologically, tumor cells were stained positive for chromogranin A, neuron specific enolase, CD56, and S-100. Careful examinations before and after the operation revealed no other possible origin of the tumor. Based on these findings, the tumor was diagnosed as a primary hepatic carcinoid. This is a report of a rare case of a primary hepatic carcinoid tumor with a discussion of several other relevant reports.

摘要

我们报告一例发生在一名47岁男性身上的原发性肝类癌肿瘤。该患者因上腹部疼痛前来我院就诊。腹部超声、计算机断层扫描和磁共振成像显示肝脏右叶有一个大肿块。FDG-PET显示右肝叶有18F-FDG摄取。肿瘤为实性肿块,伴有囊性成分,直径约15厘米。我们进行了肝脏扩大右叶切除术。切除标本为具有囊性成分和出血性病变的实性肿瘤。显微镜检查发现肿瘤细胞有圆形核并形成小梁状结构。免疫组织化学检查显示,肿瘤细胞嗜铬粒蛋白A、神经元特异性烯醇化酶、CD56和S-100染色呈阳性。手术前后的仔细检查未发现肿瘤的其他可能来源。基于这些发现,该肿瘤被诊断为原发性肝类癌。本文报告了一例罕见的原发性肝类癌肿瘤病例,并对其他几篇相关报告进行了讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0210/2895173/57fdd75a9777/crg0003-0030-f01.jpg

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