在VSRAD分析中，针对3特斯拉磁共振成像定制特定的正常数据库是必不可少的。
Customization of normal data base specific for 3-tesla MRI is mandatory in VSRAD analysis.
作者信息
Goto Masami, Suzuki Yuuichi, Abe Osamu, Hayashi Naoto, Aoki Shigeki, Mori Harushi, Masumoto Tomohiko, Watanabe Yasushi, Satake Yoshirou, Ino Kenji, Yano Keiichi, Iida Kyouhito, Mima Kazuo, Ohtomo Kuni
机构信息
Department of Radiological Technology, University of Tokyo Hospital, Tokyo, Japan.
出版信息
Radiol Phys Technol. 2008 Jul;1(2):196-200. doi: 10.1007/s12194-008-0027-0. Epub 2008 Jun 17.
A voxel-based specific regional analysis system for Alzheimer's disease (VSRAD) was used for quantitative analysis of parahippocampal atropy with 1.5-tesla (T) MRI in a voxel-wise manner. The analysis of images acquired under a different imaging condition provides an error factor that has a calculated value. Clinical application of 3T-MRI is necessary for establishing a normal data base (N-DB) specific for 3T-MRI data, which permits appropriate application of VSRAD. We established an N-DB specific for 3T-MRI for use in VSRAD. The "Z-score of the parahippocampal gyrus" was 0.79 +/- 0.32, and the N-DB of each age group did not have a big deflection when we analyzed a group of physically unimpaired persons in an N-DB specific for 3T-MRI. Therefore, we were able to confirm the validity of the customized N-DB. The "Z-score of the parahippocampal gyrus" was 1.62 +/- 0.47 for the N-DB of VSRAD. The numerical value was high for the group of physically unimpaired persons.
基于体素的阿尔茨海默病特定区域分析系统（VSRAD）用于以体素方式对1.5特斯拉（T）磁共振成像（MRI）的海马旁萎缩进行定量分析。对在不同成像条件下采集的图像进行分析会提供一个具有计算值的误差因子。3T-MRI的临床应用对于建立特定于3T-MRI数据的正常数据库（N-DB）是必要的，这使得VSRAD能够得到恰当应用。我们建立了一个特定于3T-MRI的N-DB用于VSRAD。在特定于3T-MRI的N-DB中分析一组身体无损伤的人时，海马旁回的“Z分数”为0.79±0.32，且各年龄组的N-DB没有很大偏差。因此，我们能够确认定制的N-DB的有效性。VSRAD的N-DB的海马旁回“Z分数”为1.62±0.47。对于身体无损伤的人群，该数值较高。
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