Department of Otolaryngology, Emory University, Atlanta, GA 30322, USA.
Curr Allergy Asthma Rep. 2011 Jun;11(3):230-5. doi: 10.1007/s11882-011-0181-z.
A multitude of potential etiologies exist for rhinitis and rhinosinusitis. These sinonasal disorders are heterogeneous entities that are best understood by evaluating the causative factors in each individual patient. More precise diagnosis permits accurate and effective treatment. The association of allergy with sinonasal symptoms has been described for decades; however, the specific relationship between allergy, rhinitis, and rhinosinusitis is complex. Considering allergy in terms of a systemic atopic disorder, along with a local inflammatory process mediated by IgE production in sinonasal tissues, is helpful in unveiling the complex connection between allergy, rhinitis, and rhinosinusitis. This article reviews recent literature regarding local IgE and sinonasal inflammatory conditions.
变应性鼻炎和鼻-鼻窦炎有许多潜在的病因。这些鼻-鼻窦疾病是异质性的实体，通过评估每个患者的致病因素，才能更好地理解。更精确的诊断可以实现准确和有效的治疗。几十年来，人们已经描述了过敏与鼻-鼻窦症状之间的关联；然而，过敏、鼻炎和鼻-鼻窦炎之间的具体关系是复杂的。从全身性特应性疾病以及 IgE 在鼻-鼻窦组织中产生的局部炎症过程的角度来考虑过敏，有助于揭示过敏、鼻炎和鼻-鼻窦炎之间的复杂联系。本文综述了有关局部 IgE 和鼻-鼻窦炎症状态的最新文献。
