Cardiac Ultrasound Laboratory, Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
Heart Fail Clin. 2011 Jul;7(3):313-21. doi: 10.1016/j.hfc.2011.03.003.
Chemotherapy-induced cardiotoxicity has become a significant public health issue. Left ventricular ejection fraction is routinely used to monitor cardiotoxicity but fails to detect subtle alterations in cardiac function. Improvements in the measurement of left ventricular ejection fraction, physical or pharmacologic stressors, and novel cardiac functional indices may be useful in the detection of cardiotoxicity. The improvements in the detection and therapy of cancer have led to the emergence of chemotherapy-induced cardiotoxicity. New echocardiographic techniques may be useful in the detection of patients undergoing chemotherapy treatments who could benefit from alternative cancer treatments, therefore decreasing the incidence of cardiotoxicity.
化疗引起的心脏毒性已成为一个重大的公共卫生问题。左心室射血分数通常用于监测心脏毒性，但无法检测到心脏功能的细微变化。左心室射血分数测量的改进、物理或药物应激以及新的心脏功能指数可能有助于检测心脏毒性。癌症检测和治疗的改进导致了化疗引起的心脏毒性的出现。新的超声心动图技术可能有助于检测接受化疗治疗的患者，这些患者可能受益于替代癌症治疗，从而降低心脏毒性的发生率。
