Dubrey Simon William, Pearse Simon, Dahdal Maher, Grocott-Mason Richard, Dalby Miles, Mittal Tarun
Cardiology Department, Hillingdon Hospital, Uxbridge, Middlesex, UK.
BMJ Case Rep. 2011 Aug 31;2011:bcr0720114487. doi: 10.1136/bcr.07.2011.4487.
The authors describe two cases of massive mitral annular calcification, initially picked up on echocardiography and suspected of being neoplastic. Subsequent evaluation by CT scanning confirmed the location, aetiology, structure and diagnosis. Both cases demonstrated large masses, with calcification of varying density. This is likely explained by the presence of the previously reported amorphous caseous material demonstrated to be present within such mass structures. Such a feature is described as caseous degeneration. Both patients described have been managed conservatively with medical therapy, predominantly due to their age and general frailty.
作者描述了两例严重的二尖瓣环钙化病例,最初通过超声心动图发现并怀疑为肿瘤性病变。随后的CT扫描评估证实了病变的位置、病因、结构及诊断。两例均显示有大的肿块,伴有密度各异的钙化。这可能是由于此前报道的无定形干酪样物质存在于此类肿块结构中所致。这种特征被描述为干酪样变性。所描述的这两位患者均因年龄及身体普遍虚弱而接受了以药物治疗为主的保守治疗。