用于生物医学应用的新型金属合金的开发。

Development of new metallic alloys for biomedical applications.

机构信息

Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan.

出版信息

Acta Biomater. 2012 Nov;8(11):3888-903. doi: 10.1016/j.actbio.2012.06.037. Epub 2012 Jul 15.

Abstract

New low modulus β-type titanium alloys for biomedical applications are still currently being developed. Strong and enduring β-type titanium alloy with a low Young's modulus are being investigated. A low modulus has been proved to be effective in inhibiting bone atrophy, leading to good bone remodeling in a bone fracture model in the rabbit tibia. Very recently β-type titanium alloys with a self-tunable modulus have been proposed for the construction of removable implants. Nickel-free low modulus β-type titanium alloys showing shape memory and super elastic behavior are also currently being developed. Nickel-free stainless steel and cobalt-chromium alloys for biomedical applications are receiving attention as well. Newly developed zirconium-based alloys for biomedical applications are proving very interesting. Magnesium-based or iron-based biodegradable biomaterials are under development. Further, tantalum, and niobium and its alloys are being investigated for biomedical applications. The development of new metallic alloys for biomedical applications is described in this paper.

摘要

新型医用低模量β型钛合金仍在研发中。目前正在研究具有高强度和耐久性的低模量β型钛合金。研究表明,低模量可有效抑制骨萎缩,促进兔胫骨骨折模型中的骨重塑。最近,具有自调节模量的β型钛合金已被提议用于可移动植入物的构建。具有形状记忆和超弹性的无镍低模量β型钛合金也在开发中。无镍不锈钢和用于生物医学应用的钴铬合金也受到关注。新型医用锆基合金也非常有趣。用于生物医学应用的镁基或铁基可生物降解生物材料正在开发中。此外,钽、铌及其合金也在生物医学应用方面得到了研究。本文介绍了用于生物医学应用的新型金属合金的开发。

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