与甲基三醇硼锂的交叉偶联反应。
Cross-coupling reaction with lithium methyltriolborate.
机构信息
Frontier Chemistry Center, Faculty of Engineering, Hokkaido University, Sapporo 060-8628, Japan.
出版信息
Molecules. 2012 Dec 28;18(1):430-9. doi: 10.3390/molecules18010430.
We newly developed lithium methyltriolborate as an air-stable white solid that is convenient to handle. The good performance of this triolborate for metal-catalyzed bond-forming reactions was demonstrated in palladium-catalyzed cross-coupling reactions with haloarenes. Cross-coupling reaction of [MeB(OCH₂)₃CCH₃]Li with aryl halides occurred in the presence of Pd(OAc)₂/RuPhos complex in refluxing MeOH/H₂O and the absence of bases.
我们新开发的甲基三醇硼酸锂是一种方便处理的空气稳定的白色固体。这种三醇硼酸锂在钯催化的键形成反应中表现出良好的性能，可用于卤代芳烃的钯催化交叉偶联反应。在回流的 MeOH/H₂O 中，在 Pd(OAc)₂/RuPhos 配合物的存在下，[MeB(OCH₂)₃CCH₃]Li 与芳基卤化物的交叉偶联反应发生，无需碱的参与。
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