University of Ilorin, Ilorin, Nigeria.
Otolaryngol Head Neck Surg. 2013 Apr;148(4):557-63. doi: 10.1177/0194599813477605. Epub 2013 Feb 21.
To determine the prevalence of allergic rhinitis in our study population and the correlation between the Score for Allergic Rhinitis (SFAR) and nasal smear eosinophil count.
Cross-sectional study.
Ear, nose, and throat clinic, University of Ilorin Teaching Hospital, Nigeria; a 450-bed tertiary health facility.
Two hundred seventy-five consecutive, consenting patients who presented with nasal symptoms.
Information on the 8-parameter symptom score was collected using a semistructured questionnaire by interview. Nasal smear slides were air dried, fixed with 95% alcohol, stained using May-Grünwald-Giemsa stain, and examined under a light microscope.
Of the 275 participants seen during the 1-year study, 116 (42.2%) were males. The mean ± SD age was 38.5 ± 16.3 (range, 14-75) years. Eighty-one (29.5%) were diagnosed with allergic rhinitis using a nasal smear eosinophil count. The most common symptom was excessive sneezing, involving 93% of patients with allergic rhinitis (P < .001). The prevalence of allergic rhinitis using SFAR was 31.6%. The SFAR cutoff was set at >8 (P < .001). The sensitivity and specificity for SFAR were 94.8% (confidence interval [CI], 90.5%-97.4%) and 95.1% (CI, 87.2%-98.4%), respectively. A high Spearman's correlation (0.88) was obtained for SFAR when correlated with nasal smear eosinophil count.
The prevalence of allergic rhinitis using SFAR was 31.6%. The study shows that SFAR can be used as a simple, valid diagnostic tool in allergic rhinitis. This is important in rural settings where access to laboratory investigations might not be readily available.
确定我们研究人群中过敏性鼻炎的患病率,以及过敏性鼻炎评分(SFAR)与鼻拭子嗜酸性粒细胞计数之间的相关性。
横断面研究。
尼日利亚伊洛林大学教学医院耳鼻喉科,一家拥有 450 张床位的三级保健机构。
275 名连续就诊并同意参加的出现鼻部症状的患者。
通过半结构式问卷通过访谈收集 8 项症状评分信息。鼻拭子涂片空气干燥,用 95%乙醇固定,用梅-格染色,在光镜下检查。
在为期 1 年的研究中,275 名参与者中有 116 名(42.2%)为男性。平均年龄±标准差为 38.5±16.3(范围 14-75)岁。81 名(29.5%)患者根据鼻拭子嗜酸性粒细胞计数诊断为过敏性鼻炎。最常见的症状是过度打喷嚏,涉及 93%的过敏性鼻炎患者(P<.001)。使用 SFAR 的过敏性鼻炎患病率为 31.6%。SFAR 截断值设为>8(P<.001)。SFAR 的灵敏度和特异性分别为 94.8%(置信区间[CI],90.5%-97.4%)和 95.1%(CI,87.2%-98.4%)。SFAR 与鼻拭子嗜酸性粒细胞计数相关性的斯皮尔曼等级相关系数为 0.88。
使用 SFAR 的过敏性鼻炎患病率为 31.6%。研究表明,SFAR 可作为过敏性鼻炎的一种简单、有效的诊断工具。这在实验室检查可能不易获得的农村地区尤为重要。