Soran Atilla, Ibrahim Ahmad, Kanbour Malak, McGuire Kandace, Balci Fatih L, Polat Ayfer K, Thomas Christine, Bonaventura Marguerite, Ahrendt Gretchen, Johnson Ronald
Department of Surgical Oncology, Breast Program, University of Pittsburgh, Magee-Womens Hospital, UPMC, Pittsburgh, PA.
Am J Clin Oncol. 2015 Apr;38(2):179-83. doi: 10.1097/COC.0b013e318292f8a7.
PURPOSE: Studies demonstrate an increasing rate of contralateral prophylactic mastectomy (CPM). The purpose of this study is to evaluate decision making and factors influencing women's long-term satisfaction with CPM. Descriptive analysis is used to analyze the results of our designed questionnaire approved by our Institutional Review Board. METHODS: We searched our institutional cancer registry for patients diagnosed with breast cancer between 2000 and 2010. The studied time frame is of significance as this study is the first to measure response rate in questions examining patient satisfaction for >1 year after undergoing CPM. The questionnaire was mailed to all consented participants to examine factors contributing to the choice of CPM and postoperative satisfaction. RESULTS: Of the 206 women included in the study, 147 were aged up to 50 years. Majority of women who underwent CPM in this cohort was with a bachelor's degree or higher, married or partnered women, and women earning >$60,000/y. Almost all women were "happy with overall surgery" and would recommend CPM to other patients. Psychological factors, such as fear of recurrence, were more commonly associated with the decision for CPM in patients with invasive carcinoma. Opinions of partners, relatives, friends, and physicians further contributed to the decision to undergo surgery. The availability of reconstruction was also an influential factor in the overall decision. CONCLUSIONS: The majority of our study participants experienced long-term satisfaction with the surgical procedure of CPM. From our analysis, we can confidently say that fear of cancer recurrence and the opinions of others, among other factors, were influencing contributors toward the decision of undergoing CPM.
目的:研究表明对侧预防性乳房切除术(CPM)的实施率在不断上升。本研究的目的是评估决策过程以及影响女性对CPM长期满意度的因素。采用描述性分析来分析我们设计的经机构审查委员会批准的问卷结果。 方法:我们在机构癌症登记处搜索了2000年至2010年间被诊断为乳腺癌的患者。所研究的时间框架具有重要意义,因为本研究是首个测量CPM术后1年以上患者满意度相关问题的应答率的研究。问卷被邮寄给所有同意参与的参与者,以调查促成CPM选择和术后满意度的因素。 结果:在纳入研究的206名女性中,147名年龄在50岁及以下。该队列中接受CPM的女性大多数拥有学士学位或更高学历,已婚或有伴侣,年收入超过6万美元。几乎所有女性都“对整体手术满意”,并会向其他患者推荐CPM。心理因素,如对复发的恐惧,在浸润性癌患者中更常与CPM的决策相关。伴侣、亲属、朋友和医生的意见进一步促成了手术决策。重建的可行性也是总体决策中的一个影响因素。 结论:我们的大多数研究参与者对CPM手术过程感到长期满意。通过我们的分析,我们可以有信心地说,对癌症复发的恐惧和他人的意见等因素是影响接受CPM决策的因素。