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阻塞性睡眠呼吸暂停低通气综合征患者小扁桃体行悬雍垂腭咽成形术后上气道解剖结构的变化。

Upper airway anatomical changes after velopharyngeal surgery in obstructive sleep apnea patients with small tonsils.

机构信息

Department of Otolaryngology, Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

出版信息

Otolaryngol Head Neck Surg. 2013 Aug;149(2):335-41. doi: 10.1177/0194599813492113. Epub 2013 Jun 3.

DOI:10.1177/0194599813492113
PMID:23733892
Abstract

OBJECTIVE

To evaluate the relationships between anatomical changes and treatment outcomes after velopharyngeal surgery in obstructive sleep apnea (OSA) patients with small tonsils (grade 0-2 on the Brodsky scale).

STUDY DESIGN

Case series with planned data collection.

SETTING

University medical center.

SUBJECTS AND METHODS

Thirty-six OSA patients with small tonsils underwent velopharyngeal surgery including revised uvulopalatopharyngoplasty with uvula preservation and transpalatal advancement pharyngoplasty. Pre- and postoperative upper airway 3-dimensional computed tomography and polysomnography findings were obtained for comparison and analysis.

RESULTS

The overall apnea hypopnea index (AHI) decreased from 56.8 (interquartile range, 37.5-70.1) preoperatively to 16.1 (10.8-33.5) postoperatively (P < .001). The change in minimal cross-sectional area of the velopharynx (VmCSA) was independently associated with the change in AHI (P = .001, R (2) = 0.271). Preoperative VmCSA was the only preoperative anatomical variable that was an independent predictor of change in VmCSA (P = .009, R (2) = 0.184). Postoperative VmCSA was independently associated with postoperative AHI (P < .001, R (2) = 0.341).

CONCLUSION

In patients with small tonsils, an adequate increase in VmCSA is associated with a successful outcome after surgery. Patients with a relatively small preoperative VmCSA are more likely to have favorable anatomical changes after surgery.

摘要

目的

评估扁桃体分级为 0-2 级(Brodsky 分级)的阻塞性睡眠呼吸暂停(OSA)患者咽成形术后解剖结构变化与治疗效果的关系。

研究设计

有计划数据收集的病例系列。

设置

大学医学中心。

受试者和方法

36 例扁桃体较小的 OSA 患者接受了包括保留悬雍垂的改良悬雍垂腭咽成形术和经硬腭推进咽成形术在内的咽成形术。比较和分析术前和术后上气道 3 维计算机断层扫描和多导睡眠图检查结果。

结果

总的呼吸暂停低通气指数(AHI)从术前的 56.8(四分位间距,37.5-70.1)降至术后的 16.1(10.8-33.5)(P<0.001)。最小腭咽横截面积(VmCSA)的变化与 AHI 的变化独立相关(P=0.001,R(2)=0.271)。术前 VmCSA 是唯一与 VmCSA 变化独立相关的术前解剖学变量(P=0.009,R(2)=0.184)。术后 VmCSA 与术后 AHI 独立相关(P<0.001,R(2)=0.341)。

结论

在扁桃体较小的患者中,VmCSA 的充分增加与手术成功相关。术前 VmCSA 相对较小的患者术后更有可能发生解剖结构的有利变化。