Stępień Renata, Głuszek Stanisław, Kozieł Dorota, Kaczmarczyk Małgorzata
Pol Przegl Chir. 2014 Mar;86(3):132-40. doi: 10.2478/pjs-2014-0025.
The increase in prevalence of chronic diseases in old age is concomitant with increasing risk of neoplasms requiring surgical treatment. The aim of the study was to assess the indications, treatment outcomes, complications and mortality associated with surgical treatment of patients aged 85 or more, with special consideration of colorectal cancer.
The retrospective analysis involved a group of 94 patents (x = 88.9) aged 85 or more and treated surgically in the years 2006-2011. The results were compared with a randomly selected control group of 91 patients aged 45-75 (x = 56,4) and treated surgically in the same period.
Neoplastic diseases in the study group (85 ≥), compared with the control group (< 75), were a significantly more frequent indication for surgical treatment (p < 0.01). In the group of patients aged 85 or more, the most frequent indications for elective surgery were neoplasms of the skin and subcutaneous tissue (26.4%) and gastrointestinal neoplasms, mainly colorectal cancer (23.5%). Postoperative complications were significantly more frequent (p < 0.01) among patients aged 85 or more (n = 27; 34.8%) than in the younger group (n = 17; 18.7%). Postoperative mortality among patients undergoing emergency surgery was significantly higher (p < 0.05) in the senior group than in the group of younger patients.
Surgical procedures in patients aged 85 or more are most frequently performed in the emergency setting, and their most common cause are neoplastic diseases. Emergency surgical treatment in patients aged 85 or more is associated with a significantly higher risk, compared with younger age groups, of developing multi-organ postoperative complications, usually leading to death. Elective surgical treatment in patients aged 85+ after appropriate preoperative preparation and in the group of younger patients shows similar early outcomes.
老年慢性病患病率的增加与需要手术治疗的肿瘤风险增加相伴。本研究的目的是评估85岁及以上患者手术治疗的适应症、治疗结果、并发症及死亡率,特别考虑结直肠癌。
回顾性分析涉及2006 - 2011年间接受手术治疗的94例年龄在85岁及以上的患者(平均年龄88.9岁)。将结果与同期随机选取的91例年龄在45 - 75岁(平均年龄56.4岁)的对照组患者进行比较。
与对照组(年龄<75岁)相比,研究组(年龄≥85岁)因肿瘤疾病接受手术治疗的比例显著更高(p<0.01)。在85岁及以上的患者组中,择期手术最常见的适应症是皮肤和皮下组织肿瘤(26.4%)以及胃肠道肿瘤,主要是结直肠癌(23.5%)。85岁及以上患者(n = 27;34.8%)术后并发症的发生率显著高于年轻组(n = 17;18.7%)(p<0.01)。老年组急诊手术患者的术后死亡率显著高于年轻患者组(p<0.05)。
85岁及以上患者的手术大多在急诊情况下进行,最常见的原因是肿瘤疾病。与年轻患者组相比,85岁及以上患者的急诊手术治疗发生多器官术后并发症的风险显著更高,通常会导致死亡。85岁及以上患者在进行适当的术前准备后进行择期手术,其早期结果与年轻患者组相似。