Endris Mengistu, Moges Feleke, Belyhun Yeshambel, Woldehana Eleni, Esmael Ahmed, Unakal Chandrashekhar
School of Biomedical and Laboratory Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia.
School of Biomedical and Laboratory Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia ; Institute of Virology, Faculty of Medicine, University of Leipzig, Leipzig, Germany.
Tuberc Res Treat. 2014;2014:726193. doi: 10.1155/2014/726193. Epub 2014 May 5.
Objectives. The aim of this study was to assess treatment outcome and associated risk factors among TB patients registered for anti-TB treatment at Enfraz health center, northwest Ethiopia. Methods. A five-year retrospective data (2007-2011) of tuberculosis patients (n = 417) registered for anti-TB treatment at Enfraz health center, northwest Ethiopia, were reviewed. Tuberculosis outcomes were following the WHO guidelines. Data were entered and analyzed using SPSS version 20. Results. Among 417 study participants, 95 (22.8%), 141 (33.8%), and 181 (43.4%) were smear-positive, smear-negative, and extrapulmonary tuberculosis patients, respectively. Of the 417 study participants, 206 (49.4%) were tested for HIV. The TB-HIV coinfection was 24/206 (11.7%). Seventeen study participants (4.2%) were transferred to other health facilities. Among the 400 study participants, 379 (94.8%) had successful treatment outcome (302 treatment completed and 77 cured). The overall death, default, and failure rates were 3.4%, 0.5%, and 1.2%, respectively. There was no significant association between sex, age, residence, type of TB, HIV status, and successful TB treatment outcome. Conclusion. Treatment outcome of patients who attended their anti-TB treatment at Enfraz health center was successful. Therefore, this treatment success rate should be maintained and strengthened to achieve the millennium development goal.
目的。本研究旨在评估在埃塞俄比亚西北部恩弗拉兹健康中心登记接受抗结核治疗的结核病患者的治疗结果及相关危险因素。方法。回顾了埃塞俄比亚西北部恩弗拉兹健康中心登记接受抗结核治疗的结核病患者（n = 417）的五年回顾性数据（2007 - 2011年）。结核病结果遵循世界卫生组织指南。使用SPSS 20版输入并分析数据。结果。在417名研究参与者中，分别有95名（22.8%）、141名（33.8%）和181名（43.4%）为涂片阳性、涂片阴性和肺外结核病患者。在417名研究参与者中，206名（49.4%）接受了HIV检测。结核 - HIV合并感染率为24/206（11.7%）。17名研究参与者（4.2%）被转到其他医疗机构。在400名研究参与者中，379名（94.8%）获得了成功的治疗结果（302名完成治疗，77名治愈）。总体死亡率、失访率和治疗失败率分别为3.4%、0.5%和1.2%。性别、年龄、居住地、结核病类型、HIV状态与成功的结核病治疗结果之间无显著关联。结论。在恩弗拉兹健康中心接受抗结核治疗的患者治疗结果是成功的。因此，应维持并加强这一治疗成功率以实现千年发展目标。
