用于单分散 PEG-PLGA 纳米粒规模化生产的三维闪流微流控反应器。
Three-dimensional flash flow microreactor for scale-up production of monodisperse PEG-PLGA nanoparticles.
机构信息
Center of Applied Microfluidic Chemistry (CAMC), Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, 790-784, Republic of Korea.
出版信息
Lab Chip. 2014 Oct 21;14(20):3987-92. doi: 10.1039/c4lc00700j.
PMID:25133684
Abstract
We present a pressure-tolerant 3D parallel polyimide (PI) film microreactor operating at up to ~160 bars with direct 3D flow focusing geometry for mass production of PEG-PLGA nanoparticles in a ~10(1) gram-scale (g h(-1)).
摘要
我们提出了一种耐高压的 3D 平行聚酰亚胺（PI）薄膜微反应器，其工作压力高达约 160 巴，采用直接 3D 流聚焦几何结构，可大规模生产 PEG-PLGA 纳米颗粒（~10(1)克/小时（g h(-1)））。
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