Reginald P W, Adams J, Franks S, Wadsworth J, Beard R W
St Mary's Hospital Medical School, London, Department of Obstetrics and Gynaecology.
Br J Obstet Gynaecol. 1989 Oct;96(10):1148-52. doi: 10.1111/j.1471-0528.1989.tb03189.x.
Ovarian function was suppressed with 30 mg of medroxyprogesterone acetate, daily for 6 months, in 22 women with lower abdominal pain due to pelvic congestion. There was reduction in pelvic congestion demonstrated by venography in 17 of the 22 women, and in 16 this was associated with induction of amenorrhoea which suggests that effective ovarian suppression is an important component of successful treatment. In the 17 women who showed a reduction in venogram score, the median change in pain score was 75% compared with only 29% in the five women with no change in venogram score (P less than 0.01). This significant association between reduction in pelvic congestion and pain indicates that pelvic congestion is likely to be the cause of pain in these women and that treatment with medroxyprogesterone acetate could be of value.
对22名因盆腔充血导致下腹部疼痛的女性，每天给予30毫克醋酸甲羟孕酮抑制卵巢功能，持续6个月。22名女性中有17名经静脉造影显示盆腔充血减轻，其中16名出现闭经，这表明有效的卵巢抑制是成功治疗的重要组成部分。在静脉造影评分降低的17名女性中，疼痛评分的中位数变化为75%，而静脉造影评分无变化的5名女性中这一数字仅为29%（P<0.01）。盆腔充血减轻与疼痛之间的这种显著关联表明，盆腔充血可能是这些女性疼痛的原因，醋酸甲羟孕酮治疗可能有价值。
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