采用鼻中隔瓣重建的内镜下前颅底手术的鼻窦结局:一项前瞻性研究。

Sinonasal outcomes following endoscopic anterior skull base surgery with nasoseptal flap reconstruction: a prospective study.

作者信息

Hanson M, Patel P M, Betz C, Olson S, Panizza B, Wallwork B

机构信息

Department of Otolaryngology,Head and Neck Surgery,Princess Alexandra Hospital,Woolloongabba,Australia.

School of Medicine,University of Queensland,Woolloongabba,Australia.

出版信息

J Laryngol Otol. 2015 Jul;129 Suppl 3:S41-6. doi: 10.1017/S002221511500047X. Epub 2015 Mar 3.

Abstract

OBJECTIVE

To assess nasal morbidity resulting from nasoseptal flap use in the repair of skull base defects in endoscopic anterior skull base surgery.

METHODS

Thirty-six patients awaiting endoscopic anterior skull base surgery were prospectively recruited. A nasoseptal flap was used for reconstruction in all cases. Patients were assessed pre-operatively and 90 days post-operatively via the Sino-Nasal Outcome Test 20 questionnaire and visual analogue scales for nasal obstruction, pain, secretions and smell; endoscopic examination findings and mucociliary clearance times were also recorded.

RESULTS

Sino-Nasal Outcome Test 20 questionnaire data and visual analogue scale scores for pain, smell and secretions showed no significant differences between pre- and post-operative outcomes, with visual analogue scale scores for nasal obstruction actually showing a significant improvement (p = 0.0007). A significant deterioration for both flap and non-flap sides was demonstrated post-operatively on endoscopic examination (p = 0.002 and p = 0.02 respectively).

CONCLUSION

Whilst elevation of a nasoseptal flap in endoscopic surgery of the anterior skull base engendered significant clinical deterioration on examination post-operatively, quality of life outcomes showed that no such deterioration was subjectively experienced by the patient. In fact, there was significant nasal airway improvement following nasoseptal flap reconstruction.

摘要

目的

评估在内镜下前颅底手术中使用鼻中隔瓣修复颅底缺损所导致的鼻腔病变情况。

方法

前瞻性招募36例等待内镜下前颅底手术的患者。所有病例均使用鼻中隔瓣进行重建。术前及术后90天通过鼻-鼻窦结局测试20问卷以及鼻塞、疼痛、分泌物和嗅觉的视觉模拟量表对患者进行评估;还记录了内镜检查结果和黏液纤毛清除时间。

结果

鼻-鼻窦结局测试20问卷数据以及疼痛、嗅觉和分泌物的视觉模拟量表评分在术前和术后结果之间无显著差异,而鼻塞的视觉模拟量表评分实际上显示出显著改善(p = 0.0007)。术后内镜检查显示,瓣侧和非瓣侧均有显著恶化(分别为p = 0.002和p = 0.02)。

结论

虽然在前颅底内镜手术中提起鼻中隔瓣在术后检查时导致了显著的临床恶化,但生活质量结果表明患者并未主观感受到此类恶化。事实上,鼻中隔瓣重建术后鼻气道有显著改善。

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