Khurana Bisman, Lomash Avinash, Khalil Sumaira, Bhattacharya Malvika, Rajeshwari K, Kapoor Seema
Division of Genetics, Department of Pediatrics, Maulana Azad Medical College, Associated Lok Nayak Hospital, Bahadur Shah Zafar Marg, New Delhi, 110 002, India.
Indian J Gastroenterol. 2015 Mar;34(2):112-6. doi: 10.1007/s12664-015-0563-6. Epub 2015 May 9.
Lifelong dietary abstinence of gluten is the only treatment available for celiac disease. This is not only challenging but also leads to several psychosocial morbidities and affects the quality of life of children and their parents.
An observational study was conducted on 50 children (5-18 years) diagnosed with celiac disease on gluten-free diet for at least 6 months and their parents to evaluate of the impact of celiac disease and its dietary manipulation on them. The quality of life was assessed by applying celiac disease-specific questionnaire. Dietary compliant and noncompliant groups were compared to assess the factors leading to poor compliance. Anthropometric parameters were utilized to ascertain clinical response.
Fifty children with a mean age of 9.06 years were enrolled. Seventy-four percent of the children were compliant. In the compliant group, height and weight correlated with dietary compliance (p = 0.0087 and p = 0.023). Dietary compliance was found to be better in adolescent males and single child and those living in nuclear families. Quality of life was found to be higher among parents of noncompliant children (quality of life score: 63) as compared to the compliant children (quality of life score: 59). The acceptance of celiac disease was better among children whose parents had a higher level of education. The scale diet proved to be a useful indicator for evaluating compliance among children (p = 0.0036).
Noncompliance to gluten-free diet was noted in 24 % of children with celiac disease.
终身禁食麸质是乳糜泻唯一可用的治疗方法。这不仅具有挑战性，还会导致多种心理社会疾病，并影响儿童及其父母的生活质量。
对50名（5至18岁）被诊断为乳糜泻且已采用无麸质饮食至少6个月的儿童及其父母进行了一项观察性研究，以评估乳糜泻及其饮食控制对他们的影响。通过应用乳糜泻特异性问卷来评估生活质量。比较饮食依从组和不依从组，以评估导致依从性差的因素。利用人体测量参数来确定临床反应。
招募了平均年龄为9.06岁的50名儿童。74%的儿童依从饮食。在依从组中，身高和体重与饮食依从性相关（p = 0.0087和p = 0.023）。发现青少年男性、独生子女以及生活在核心家庭中的儿童饮食依从性更好。发现不依从儿童的父母的生活质量得分（生活质量得分：63）高于依从儿童（生活质量得分：59）。父母受教育程度较高的儿童对乳糜泻的接受度更好。量表饮食被证明是评估儿童依从性的有用指标（p = 0.0036）。
24%的乳糜泻儿童存在不依从无麸质饮食的情况。
