光遗传学与神经科学的未来。

Optogenetics and the future of neuroscience.

机构信息

MIT Media Lab and McGovern Institute, Departments of Brain and Cognitive Sciences and Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

出版信息

Nat Neurosci. 2015 Sep;18(9):1200-1. doi: 10.1038/nn.4094.

Abstract

Over the last 10 years, optogenetics has become widespread in neuroscience for the study of how specific cell types contribute to brain functions and brain disorder states. The full impact of optogenetics will emerge only when other toolsets mature, including neural connectivity and cell phenotyping tools and neural recording and imaging tools. The latter tools are rapidly improving, in part because optogenetics has helped galvanize broad interest in neurotechnology development.

摘要

在过去的 10 年中,光遗传学在神经科学领域得到了广泛应用,用于研究特定细胞类型如何对大脑功能和大脑障碍状态做出贡献。只有当其他工具集(包括神经连接和细胞表型工具以及神经记录和成像工具)成熟时,光遗传学的全部影响才会显现出来。后一类工具正在迅速改进,部分原因是光遗传学有助于激发人们对神经技术发展的广泛兴趣。

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