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反式脂肪政策在减少英格兰冠心病死亡率方面的社会经济不平等现象的潜力:成本效益建模研究。

Potential of trans fats policies to reduce socioeconomic inequalities in mortality from coronary heart disease in England: cost effectiveness modelling study.

作者信息

Allen Kirk, Pearson-Stuttard Jonathan, Hooton William, Diggle Peter, Capewell Simon, O'Flaherty Martin

机构信息

Lancaster Medical School, Lancaster University, Lancaster LA1 4YW, UK Department of Public Health and Policy, Liverpool University, Liverpool L69 3GB, UK

Division of Medical Sciences, University of Oxford, Oxford OX3 9DU, UK.

出版信息

BMJ. 2015 Sep 15;351:h4583. doi: 10.1136/bmj.h4583.

Abstract

OBJECTIVES

To determine health and equity benefits and cost effectiveness of policies to reduce or eliminate trans fatty acids from processed foods, compared with consumption remaining at most recent levels in England.

DESIGN

Epidemiological modelling study.

SETTING

Data from National Diet and Nutrition Survey, Low Income Diet and Nutrition Survey, Office of National Statistics, and health economic data from other published studies

PARTICIPANTS

Adults aged ≥25, stratified by fifths of socioeconomic circumstance.

INTERVENTIONS

Total ban on trans fatty acids in processed foods; improved labelling of trans fatty acids; bans on trans fatty acids in restaurants and takeaways.

MAIN OUTCOME MEASURES

Deaths from coronary heart disease prevented or postponed; life years gained; quality adjusted life years gained. Policy costs to government and industry; policy savings from reductions in direct healthcare, informal care, and productivity loss.

RESULTS

A total ban on trans fatty acids in processed foods might prevent or postpone about 7200 deaths (2.6%) from coronary heart disease from 2015-20 and reduce inequality in mortality from coronary heart disease by about 3000 deaths (15%). Policies to improve labelling or simply remove trans fatty acids from restaurants/fast food could save between 1800 (0.7%) and 3500 (1.3%) deaths from coronary heart disease and reduce inequalities by 600 (3%) to 1500 (7%) deaths, thus making them at best half as effective. A total ban would have the greatest net cost savings of about £265m (€361m, $415m) excluding reformulation costs, or £64m if substantial reformulation costs are incurred outside the normal cycle.

CONCLUSIONS

A regulatory policy to eliminate trans fatty acids from processed foods in England would be the most effective and equitable policy option. Intermediate policies would also be beneficial. Simply continuing to rely on industry to voluntary reformulate products, however, could have negative health and economic outcomes.

摘要

目标

与英国目前的反式脂肪酸摄入量水平相比,确定减少或消除加工食品中反式脂肪酸的政策对健康、公平性的益处以及成本效益。

设计

流行病学建模研究。

背景

来自国家饮食与营养调查、低收入饮食与营养调查、国家统计局的数据,以及其他已发表研究的卫生经济数据

研究对象

年龄≥25岁的成年人,按社会经济状况的五分之一分层。

干预措施

全面禁止加工食品中的反式脂肪酸;改进反式脂肪酸标签;禁止餐厅和外卖食品中使用反式脂肪酸。

主要结局指标

预防或推迟的冠心病死亡人数;获得的生命年数;获得的质量调整生命年数。政府和行业的政策成本;因直接医疗保健、非正式护理和生产力损失减少而节省的政策费用。

结果

全面禁止加工食品中的反式脂肪酸可能在2015年至2020年期间预防或推迟约7200例(2.6%)冠心病死亡,并使冠心病死亡率的不平等减少约3000例(15%)。改进标签或仅从餐厅/快餐中去除反式脂肪酸的政策可减少1800例(0.7%)至3500例(1.3%)冠心病死亡,并使不平等减少600例(3%)至1500例(7%)死亡,因此其效果充其量只有全面禁令的一半。全面禁令将带来最大的净成本节省,约为2.65亿英镑(3.61亿欧元,4.15亿美元)(不包括重新配方成本),如果在正常周期之外产生大量重新配方成本,则为6400万英镑。

结论

在英国实施一项监管政策,消除加工食品中的反式脂肪酸,将是最有效和公平的政策选择。中间政策也将有益。然而,仅仅继续依赖行业自愿重新配方产品可能会对健康和经济产生负面结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4238/4784770/d63a585e64c0/allk024146.f1_default.jpg

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