中国男男性行为者和男女双性恋者中的性风险行为与艾滋病毒感染：来自系统评价和荟萃分析的证据

Sexual Risk Behaviors and HIV Infection among Men Who Have Sex with Men and Women in China: Evidence from a Systematic Review and Meta-Analysis.

作者信息

Wang Hong-Yi, Xu Jun-Jie, Zou Hua-Chun, Reilly Kathleen Heather, Zhang Christiana Meng, Yun Ke, Li Yong-Ze, Jiang Yong-Jun, Geng Wen-Qing, Shang Hong, Wang Ning

机构信息

Key Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang 110001, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou 310000, China.

Kirby Institute, University of New South Wales, Sydney, NSW 2052, Australia.

出版信息

Biomed Res Int. 2015;2015:850132. doi: 10.1155/2015/850132. Epub 2015 Dec 8.

DOI:10.1155/2015/850132

PMID:26779538

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4686633/

Abstract

OBJECTIVES

To understand the current risk of HIV infection and transmission and further elucidate the underlying risk factors among men who have sex with men and women (MSMW) in China.

METHODS

Following PRISMA guidelines, we conducted a systematic review and meta-analysis of searching through Chinese and English available literature databases between January 2000 and June 2014 to identify articles.

RESULTS

Thirty-six articles (including 19,730 MSMW and 53,536 MSMO) met the selection criteria and the aggregated results found that MSMW have significantly higher HIV prevalence than MSMO (6.6% versus 5.4%, OR = 1.27, 95% CI = 1.01-1.58). A higher proportion of MSMW had commercial male partners in the past 6 months (18.3% versus 12.2%, OR = 1.56, 95% CI = 1.01-2.42). Additionally, substance use in the past 6 months was significantly more frequent among MSMW than MSMO (alcohol use: 27.1% versus 13.1%, OR = 2.53, 95% CI = 2.14-2.99; illicit drug use: 5.3% versus 2.5%, OR = 2.09, 95% CI = 1.48-2.95).

CONCLUSION

A higher proportion of commercial sex and substance use among MSMW may be a potentially indicative factor for significantly higher HIV prevalence compared to MSMO. Targeted interventions should aim at increasing the frequency of HIV/STIs screening and preventing high risk commercial sex and substance use among MSMW to decrease their HIV transmission to the general population.

摘要

目的

了解中国男男性行为者与女性发生性行为者（MSMW）当前的HIV感染和传播风险，并进一步阐明其潜在风险因素。

方法

遵循PRISMA指南，我们对2000年1月至2014年6月期间通过中英文现有文献数据库检索到的文章进行了系统综述和荟萃分析，以确定相关文章。

结果

36篇文章（包括19730名MSMW和53536名男男性行为者（MSMO））符合入选标准，汇总结果发现MSMW的HIV感染率显著高于MSMO（6.6%对5.4%，OR = 1.27，95%CI = 1.01 - 1.58）。在过去6个月中，有更高比例的MSMW有商业男性性伴（18.3%对12.2%，OR = 1.56，95%CI = 1.01 - 2.42）。此外，在过去6个月中，MSMW使用物质的情况比MSMO明显更频繁（饮酒：27.1%对13.1%，OR = 2.53，95%CI = 2.14 - 2.99；非法药物使用：5.3%对2.5%，OR = 2.09，95%CI = 1.48 - 2.95）。