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蛋白质食物组与高血压的3年发病率:来自德黑兰脂质与血糖研究的一项前瞻性研究

Protein Foods Group and 3-Year Incidence of Hypertension: A Prospective Study From Tehran Lipid and Glucose Study.

作者信息

Golzarand Mahdieh, Bahadoran Zahra, Mirmiran Parvin, Azizi Fereidoun

机构信息

Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

J Ren Nutr. 2016 Jul;26(4):219-25. doi: 10.1053/j.jrn.2016.01.017. Epub 2016 Feb 20.

Abstract

OBJECTIVES

Dietary factors play an important role in the development of hypertension (HTN). In this study, we aimed to determine the possible effect of protein foods group and its subgroups on risk of HTN after 3-year follow-up in Iranian adults.

DESIGN

Prospective study in framework of the Tehran Lipid and Glucose Study.

SUBJECTS

A total of 1,152 healthy adults, aged 20 to 84 years participated and were followed-up for 3 years.

MAIN OUTCOME MEASURE

Usual dietary intake was assessed using a 168-item validate semiquantitative food frequency questionnaire at baseline and again after 3 years. Protein foods group was considered as the sum of meats, poultry, seafood, eggs, beans and peas, nuts, and seeds. Blood pressure was measured at baseline and after 3 years, and HTN was diagnosed by the seventh report of Joint National Committee on prevention, detection, evaluation and treatment of high blood pressure (JNC-VII). To assess the odds ratio of HTN in each tertile of protein foods group and its subgroup, a multivariate logistic regression adjusted for potential confounding variables was used.

RESULTS

Mean age of participants was 36.0 ± 11.2 years, and mean intake of protein foods group was 855 ± 343 g/week (range 70.5-3,450 g/week). After 3 years of follow-up, the incidence of HTN was 12.5%. There was no significant association between dietary intakes of the protein foods group, meats, poultry, seafood, beans and peas, and nuts and seeds and the occurrence of HTN over 3 years. However, 3-year incidence of HTN was significantly decreased in the highest tertile of eggs in compared with the lowest (odds ratio: 0.54; 95% confidence interval: 0.32-0.91; P for trend = .02).

CONCLUSION

Our findings indicated that egg consumption could have favorable effect against development of HTN.

摘要

目的

饮食因素在高血压(HTN)的发生发展中起着重要作用。在本研究中,我们旨在确定蛋白质食物组及其亚组对伊朗成年人进行3年随访后高血压风险的可能影响。

设计

在德黑兰血脂与血糖研究框架内进行的前瞻性研究。

研究对象

共有1152名年龄在20至84岁之间的健康成年人参与并接受了3年的随访。

主要观察指标

在基线时和3年后,使用一份包含168个条目的经过验证的半定量食物频率问卷评估日常饮食摄入量。蛋白质食物组被视为肉类、家禽、海鲜、蛋类、豆类和豌豆、坚果及种子的总和。在基线时和3年后测量血压,并根据美国预防、检测、评估与治疗高血压联合委员会第七次报告(JNC-VII)诊断高血压。为了评估蛋白质食物组及其亚组每个三分位数中高血压的比值比,使用了对潜在混杂变量进行调整的多因素逻辑回归分析。

结果

参与者的平均年龄为36.0±11.2岁,蛋白质食物组的平均摄入量为855±343克/周(范围为70.5 - 3450克/周)。经过3年的随访,高血压的发病率为12.5%。在3年期间,蛋白质食物组、肉类、家禽、海鲜、豆类和豌豆以及坚果和种子的饮食摄入量与高血压的发生之间没有显著关联。然而,与最低三分位数相比,鸡蛋摄入量最高的三分位数中高血压的3年发病率显著降低(比值比:0.54;95%置信区间:0.32 - 0.91;趋势P值 = 0.02)。

结论

我们的研究结果表明,食用鸡蛋可能对高血压的发展具有有益作用。

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