利用小鼠脑立体定位精细图谱绘制多个听觉皮层区域的定量图谱。
Quantitative map of multiple auditory cortical regions with a stereotaxic fine-scale atlas of the mouse brain.
作者信息
Tsukano Hiroaki, Horie Masao, Hishida Ryuichi, Takahashi Kuniyuki, Takebayashi Hirohide, Shibuki Katsuei
机构信息
Department of Neurophysiology, Brain Research Institute, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata 951-8585, Japan.
Division of Neurobiology and Anatomy, Graduate School of Medicine and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata 951-8510, Japan.
出版信息
Sci Rep. 2016 Feb 29;6:22315. doi: 10.1038/srep22315.
Optical imaging studies have recently revealed the presence of multiple auditory cortical regions in the mouse brain. We have previously demonstrated, using flavoprotein fluorescence imaging, at least six regions in the mouse auditory cortex, including the anterior auditory field (AAF), primary auditory cortex (AI), the secondary auditory field (AII), dorsoanterior field (DA), dorsomedial field (DM), and dorsoposterior field (DP). While multiple regions in the visual cortex and somatosensory cortex have been annotated and consolidated in recent brain atlases, the multiple auditory cortical regions have not yet been presented from a coronal view. In the current study, we obtained regional coordinates of the six auditory cortical regions of the C57BL/6 mouse brain and illustrated these regions on template coronal brain slices. These results should reinforce the existing mouse brain atlases and support future studies in the auditory cortex.
光学成像研究最近揭示了小鼠大脑中存在多个听觉皮层区域。我们之前利用黄素蛋白荧光成像技术,在小鼠听觉皮层中证实了至少六个区域,包括前听觉场(AAF)、初级听觉皮层(AI)、次级听觉场(AII)、背前场(DA)、背中场(DM)和背后场(DP)。虽然视觉皮层和体感皮层中的多个区域已在最近的脑图谱中进行了标注和整合,但多个听觉皮层区域尚未从冠状面视角呈现。在本研究中,我们获取了C57BL/6小鼠大脑六个听觉皮层区域的区域坐标,并在冠状脑模板切片上展示了这些区域。这些结果应能加强现有的小鼠脑图谱,并支持未来对听觉皮层的研究。