Rehman Ghani Ur, Ali Mohammad, Shah Farooq, Iqbal Amjad, Ahmad Ayaz, Hayat Zafar, Islam Badshah, Ali Farman, Jamal Yousaf, Alam Sartaj, Sajjad Muhammad, Bhatti Muhammad Zeeshan
Department of Biotechnology, Bacha Khan University, Charsadda, Pakistan.
Department of Agriculture, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Biomed Res Int. 2017;2017:2416281. doi: 10.1155/2017/2416281. Epub 2017 Apr 4.
Hepatitis C (HCV) and diabetes mellitus are the two main health concerns that cause devastating health and financial worries worldwide. It has been observed in the past that both diseases have a high correlation that might be due to the abnormal conditions of the liver. But the mechanism of the prevalence of diabetes in patients with chronic HCV infection still remains unclear. In our study, we have investigated T2DM in the male and female patients at Lady Reading Hospital (LRH), Peshawar. The blood samples of both in- and outpatients were analysed in the PCR laboratories of LRH from December 2014 to April 2015. Great prevalence of diabetes in hepatitis C infected male and female patients was observed during this study. The data were collected from the patients through a preplanned questionnaire that included name of the patient, HCV, being diabetic, age, gender, location, educational background, family history of the disease, other diseases, and any treatments if taken. The results of our study have found 26.42% prevalence of T2DM in HCV infected patients. So we conclude that HCV infection may be one of the reasons that could lead to T2DM.
丙型肝炎（HCV）和糖尿病是引发全球严重健康问题和经济担忧的两大主要健康隐患。过去人们观察到这两种疾病具有高度相关性，这可能归因于肝脏的异常状况。但慢性HCV感染患者中糖尿病流行的机制仍不清楚。在我们的研究中，我们调查了白沙瓦市雷丁夫人医院（LRH）的男性和女性患者中的2型糖尿病（T2DM）情况。2014年12月至2015年4月期间，在LRH的PCR实验室对门诊和住院患者的血液样本进行了分析。在这项研究中，观察到丙型肝炎感染的男性和女性患者中糖尿病的患病率很高。通过预先设计的问卷从患者那里收集数据，问卷包括患者姓名、HCV感染情况、是否患有糖尿病、年龄、性别、地点、教育背景、疾病家族史、其他疾病以及是否接受过任何治疗。我们的研究结果发现，HCV感染患者中T2DM的患病率为26.42%。因此我们得出结论，HCV感染可能是导致T2DM的原因之一。
