沙特阿拉伯大学医院上呼吸道感染患者抗生素的使用与滥用情况:知识、态度及行为分析

Antibiotics use and misuse in upper respiratory tract infection patients: Knowledge, attitude and practice analysis in University Hospital, Saudi Arabia.

作者信息

Hajjar Waseem, Alnassar Sami, Al-Khelb Sara, Al-Mutairi Sarah, Al-Refayi Norah, Meo Sultan Ayoub

机构信息

Department of Thoracic Surgery, King Saud University, Riyadh, Kingdom of Saudi Arabia.

College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.

出版信息

J Pak Med Assoc. 2017 Sep;67(9):1387-1392.

DOI:
Abstract

OBJECTIVE

To assess the awareness and causes of antibiotics use and misuse in patients with upper respiratory tract infections.

METHODS

This cross-sectional study was conducted at King Saud University, Riyadh, Saudi Arabia, from January 2014 to December 2015, and comprised patients suffering from upper respiratory tract infections. A well-established, self-administrated questionnaire was randomly distributed to the patients. The questionnaire consisted of 3 parts: demographic variables, knowledge, and beliefs, and behaviour towards antibiotic use and misuse. SPSS 21 was used for data analysis.

RESULTS

Of the 400 participants, 193(48.25%) were males and 207(51.75%) were females. Besides, 182(45.5%) participants used antibiotics without prescription (p=0.050) and 43(10.8%) used the mover a pharmacist's advice (p=0.030). Also, 69(17.3%) participants forced the physicians to prescribe antibiotic (p=0.014), and 207(51.7%) patients stopped taking antibiotics when they felt better (p=0.007). Moreover, 180(45%) had the antibiotic stocks at home in case of emergencies. In addition, 67(16.8%) were ignoring the instructions when taking antibiotics (p=0.004). Furthermore, 48(12%) participants denied that an antibiotic could cause an allergic reaction (p=0.054) and the same number of participants believed that the effectiveness of the treatment would not be affected if a full course of antibiotic was not completed (p=0.029). In addition, 29(7.3%) participants with high educational level believed that all antibiotics did not have side-effects (p=0.002) and 71(17.8%) of them believed that if symptoms were improving the antibiotic course could be interrupted without completing (p=0.037).

CONCLUSIONS

Misconceptions existed about the use and indications of antibiotics.

摘要

目的

评估上呼吸道感染患者对抗生素使用及滥用的认知情况和原因。

方法

本横断面研究于2014年1月至2015年12月在沙特阿拉伯利雅得的沙特国王大学进行,研究对象为患有上呼吸道感染的患者。向患者随机发放一份成熟的自填式问卷。问卷由三部分组成:人口统计学变量、知识与信念以及抗生素使用和滥用的行为。使用SPSS 21进行数据分析。

结果

400名参与者中,193名(48.25%)为男性,207名(51.75%)为女性。此外,182名(45.5%)参与者无处方使用抗生素(p = 0.050),43名(10.8%)参与者未听从药剂师的建议(p = 0.030)。还有,69名(17.3%)参与者迫使医生开具抗生素(p = 0.014),207名(51.7%)患者感觉好转后就停止服用抗生素(p = 0.007)。此外,180名(45%)患者家中备有抗生素以防紧急情况。另外,67名(16.8%)患者服用抗生素时忽视说明(p = 0.004)。此外,48名(12%)参与者否认抗生素会引起过敏反应(p = 0.054),同样数量的参与者认为未完成整个抗生素疗程不会影响治疗效果(p = 0.029)。此外,29名(7.3%)高学历参与者认为所有抗生素都没有副作用(p = 0.002),其中71名(17.8%)认为如果症状改善,抗生素疗程可以中断而无需完成(p = 0.037)。

结论

关于抗生素的使用和适应证存在误解。

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