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转移性脊柱肿瘤手术后金属植入物失效的基本概念。

Basic concepts in metal work failure after metastatic spine tumour surgery.

作者信息

Kumar Naresh, Patel Ravish, Wadhwa Anshuja Charvi, Kumar Aravind, Milavec Helena Maria, Sonawane Dhiraj, Singh Gurpal, Benneker Lorin Michael

机构信息

Department of Orthopaedic Surgery, National University Hospital, Singapore, 119074, Singapore.

Department of Orthopaedic Surgery, University Orthopaedics, Hand and Reconstructive Microsurgery Cluster, 1E Kent Ridge Road, NUHS Tower Block, Level 11, Singapore, 119228, Singapore.

出版信息

Eur Spine J. 2018 Apr;27(4):806-814. doi: 10.1007/s00586-017-5405-z. Epub 2017 Dec 4.

Abstract

PURPOSE

The development of spinal implants marks a watershed in the evolution of metastatic spine tumour surgery (MSTS), which has evolved from standalone decompressive laminectomy to instrumented stabilization and decompression with reconstruction when necessary. Fusion may not be feasible after MSTS due to poor quality of graft host bed along with adjunct chemotherapy and/or radiotherapy postoperatively. With an increase in the survival of patients with spinal tumours, there is a probability of an increase in the rate of implant failure. This review aims to help establish a clear understanding of implants/constructs used in MSTS and to highlight the fundamental biomechanics of implant/construct failures.

METHODS

Published literature on implant failure after spine surgery and MSTS has been reviewed. The evolution of spinal implants and their role in MSTS has been briefly described. The review defines implant/construct failures using radiological parameters that are practical, feasible, and derived from historical descriptions. We have discussed common modes of implant/construct failure after MSTS to allow further understanding, interception, and prevention of catastrophic failure.

RESULTS

Implant failure rates in MSTS are in the range of 2-8%. Variability in patterns of failure has been observed based on anatomical region and the type of constructs used. Patients with construct/implant failures may or may not be symptomatic and present either as early (< 3months) or late failures (> 3months). It has been noted that not all the implant failures after MSTS result in revisions.

CONCLUSION

Based on the observed radiological criteria and clinical presentations, we have proposed a clinico-radiological classification for implant/construct failure after MSTS.

摘要

目的

脊柱植入物的发展标志着转移性脊柱肿瘤手术(MSTS)发展历程中的一个分水岭,该手术已从单纯的减压性椎板切除术演变为必要时进行器械固定及减压并重建。由于术后移植骨床质量差以及辅助化疗和/或放疗,MSTS后融合可能不可行。随着脊柱肿瘤患者生存率的提高,植入物失败率有可能增加。本综述旨在帮助明确了解MSTS中使用的植入物/结构,并强调植入物/结构失败的基本生物力学原理。

方法

对已发表的关于脊柱手术和MSTS后植入物失败的文献进行了综述。简要描述了脊柱植入物的发展及其在MSTS中的作用。本综述使用实际、可行且源自历史描述的放射学参数来定义植入物/结构失败。我们讨论了MSTS后植入物/结构失败的常见模式,以便进一步了解、拦截和预防灾难性失败。

结果

MSTS中的植入物失败率在2%至8%之间。根据解剖区域和所用结构类型,观察到失败模式存在差异。植入物/结构失败的患者可能有症状,也可能没有症状,表现为早期(<3个月)或晚期失败(>3个月)。值得注意的是,并非所有MSTS后的植入物失败都需要翻修。

结论

基于观察到的放射学标准和临床表现,我们提出了MSTS后植入物/结构失败的临床放射学分类。

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