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[刚果民主共和国卢本巴希儿童中与艾滋病毒自愿咨询和检测(VCT)相关的血清流行率及因素]

[Seroprevalence and factors associated with Voluntary Counselling and Testing (VCT) for HIV among children in Lubumbashi, Democratic Republic of the Congo].

作者信息

Ngwej Dieudonné Tshikwej, Mukuku Olivier, Malonga Françoise Kaj, Luboya Oscar Numbi, Kakoma Jean-Baptiste Sakatolo, Wembonyama Stanis Okitotsho

机构信息

Département de Pédiatrie, Faculté de Médecine, Université de Lubumbashi, République Démocratique du Congo.

Bureau Provincial de ICAP/RDC, Lubumbashi, République Démocratique du Congo.

出版信息

Pan Afr Med J. 2017 Sep 27;28:82. doi: 10.11604/pamj.2017.28.82.9566. eCollection 2017.

Abstract

INTRODUCTION

Despite proposals for screening infants or preschool children for HIV infection, the proportion of children who grow or die with unknown HIV status is high in the Democratic Republic of the Congo (DRC). This study aimed to determine the seroprevalence during a voluntary screening and to identify factors associated with Voluntary Counselling and Testing (VCT) for HIV in the paediatric population of non-HIV infected or non-HIV exposed infants and children in Lubumbashi, DRC.

METHODS

We conducted a cross-sectional prospective analytical study in 4 community VCT centers divided into 4 health zones in the city of Lubumbashi, DRC (Lubumbashi, Ruashi, Kampemba and Kenya) over the period 1 August 2006 - 31 September 2007. The study aimed to evaluate voluntary testing for HIV among children less than 15 years. The sociodemographic characteristics and the parameters related to Voluntary Counselling and Testing (VCT) for HIV were analyzed. Usual descriptive statistical analyses and logistic regression were perfomed.

RESULTS

Out of 463 children screened for HIV, 41 (8.9%; 95% CI: 6.5%-11.9%) were HIV positive. Voluntary Counselling and Testing (VCT) for HIV in the paediatric population of non-HIV infected or non-HIV exposed infants or children was significantly higher in children over 2 years of age (adjusted odds ratio (AOR)=3.6 [95% CI: 1,1-12,2]) when both of their parents had negative or uknown HIV status (AOR = 27.4 [95% CI: 9,4-80,0]), when either or both of their biological parents were alive (AOR = 24.9 [95% CI: 2,4-250,8]) and when screening programs were not only carried out by health professionals (AOR = 2.9 [95% CI: 1,0-7,9]).

CONCLUSION

Our study shows a high HIV prevalence among children supporting the need for VCT highly accepted by parents and tutors in the city of Lubumbashi.

摘要

引言

尽管有对婴儿或学龄前儿童进行HIV感染筛查的提议,但在刚果民主共和国(DRC),HIV感染状况不明时成长或死亡的儿童比例很高。本研究旨在确定自愿筛查期间的血清流行率,并确定在刚果民主共和国卢本巴希未感染HIV或未接触过HIV的婴儿和儿童的儿科人群中,与HIV自愿咨询检测(VCT)相关的因素。

方法

2006年8月1日至2007年9月31日期间,我们在刚果民主共和国卢本巴希市分为4个健康区的4个社区VCT中心(卢本巴希、鲁阿希、坎佩姆巴和肯尼亚)进行了一项横断面前瞻性分析研究。该研究旨在评估15岁以下儿童的HIV自愿检测情况。分析了社会人口学特征以及与HIV自愿咨询检测(VCT)相关的参数。进行了常规描述性统计分析和逻辑回归分析。

结果

在463名接受HIV筛查的儿童中,41名(8.9%;95%置信区间:6.5%-11.9%)HIV呈阳性。在未感染HIV或未接触过HIV的婴儿或儿童的儿科人群中,2岁以上儿童的HIV自愿咨询检测(VCT)显著更高(调整后的优势比(AOR)=3.6 [95%置信区间:1.1-12.2]),其父母双方HIV状况均为阴性或不明时(AOR = 27.4 [95%置信区间:9.4-80.0]),其亲生父母一方或双方在世时(AOR = 24.9 [95%置信区间:2.4-250.8]),以及筛查项目不仅由卫生专业人员开展时(AOR = 2.9 [95%置信区间:1.0-7.9])。

结论

我们的研究表明,儿童中HIV流行率很高,这支持了在卢本巴希市开展家长和监护人高度接受的VCT的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7f4/5724940/96b8e12eadb5/PAMJ-28-82-g001.jpg

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