老年髋部骨折患者术后限制负重时并发症增加:4918 例患者分析。

Increased complications in geriatric patients with a fracture of the hip whose postoperative weight-bearing is restricted: an analysis of 4918 patients.

机构信息

Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, Connecticut, USA.

出版信息

Bone Joint J. 2018 Oct;100-B(10):1377-1384. doi: 10.1302/0301-620X.100B10.BJJ-2018-0489.R1.

Abstract

AIMS

The aims of this study were to evaluate the incidence of postoperatively restricted weight-bearing and its association with outcome in patients who undergo surgery for a fracture of the hip.

PATIENTS AND METHODS

Patient aged > 60 years undergoing surgery for a hip fracture were identified in the 2016 National Surgical Quality Improvement Program (NSQIP) Hip Fracture Targeted Procedure Dataset. Analysis of the effect of restricted weight-bearing on adverse events, delirium, infection, transfusion, length of stay, return to the operating theatre, readmission and mortality within 30 days postoperatively were assessed. Multivariate regression analysis was used to adjust for confounding demographic, comorbid and procedural characteristics.

RESULTS

Of the 4918 patients who met inclusion criteria, 3668 (63.53%) were allowed to weight-bear as tolerated postoperatively. Controlling for patient and procedural factors, multivariate odds of any adverse event, major adverse event, delirium, infection, transfusion, length of stay ≥ 75th percentile (six days) and mortality within 30 days were all higher in patients with weight-bearing restrictions. Notably, there were no differences for thromboembolic events, return to the operating theatre or readmission within 30 days between the groups.

CONCLUSION

Elderly patients with a fracture of the hip with postoperative weight-bearing restrictions have a significantly greater risk of developing most adverse events compared with those who are encouraged to weight-bear as tolerated. These findings emphasize the importance of immediate weight-bearing as tolerated to optimize the outcome in these frail patients; however nearly 25% of surgeons fail to meet this evidence-based guideline. Cite this article: Bone Joint J 2018;100-B:1377-84.

摘要

目的

本研究旨在评估髋关节骨折术后限制负重的发生率及其与患者预后的关系。

方法

在 2016 年国家手术质量改进计划(NSQIP)髋关节骨折靶向手术数据集(Hip Fracture Targeted Procedure Dataset)中,确定了 60 岁以上接受髋关节骨折手术的患者。分析了限制负重对术后 30 天内不良事件、谵妄、感染、输血、住院时间、重返手术室、再入院和死亡率的影响。采用多变量回归分析调整混杂的人口统计学、合并症和手术特征。

结果

在符合纳入标准的 4918 例患者中,3668 例(63.53%)术后允许根据耐受情况负重。在控制患者和手术因素的情况下,负重受限患者发生任何不良事件、主要不良事件、谵妄、感染、输血、住院时间≥第 75 百分位数(6 天)和术后 30 天内死亡率的多变量比值均较高。值得注意的是,两组在血栓栓塞事件、术后 30 天内重返手术室或再入院方面无差异。

结论

与鼓励根据耐受情况负重的患者相比,髋关节骨折术后负重受限的老年患者发生大多数不良事件的风险显著增加。这些发现强调了立即根据耐受情况负重对优化这些脆弱患者预后的重要性;然而,近 25%的外科医生未能遵循这一基于证据的指南。

文献出处

Bone Joint J 2018;100-B:1377-84.

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