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复发性胸髓内 schwann 瘤:两例长期随访报告。

Recurrent thoracic intramedullary schwannoma: report of two cases with long term follow up.

机构信息

Department of Neurosurgery, IASA spine fellow, Park clinic, Kolkata, India.

Department of Neurosurgery, Park clinic, Kolkata, India.

出版信息

Br J Neurosurg. 2022 Oct;36(5):647-650. doi: 10.1080/02688697.2019.1566516. Epub 2019 Mar 5.

Abstract

Occurrence of intramedullary schwannomas is rare as Schwann cells are generally present in the nerve root and not in the spinal cord. To date, approximately around 60 cases of intramedullary schwannoma in patients without neurofibromatosis have been reported in the English literature, of which only eight were children. We describe two cases of thoracic intramedullary schwannomas that recurred after primary excision. A 10 years old boy presented with weakness of both lower limbs. Magnetic resonance imaging showed a D10 to D12 intramedullary lesion, which was excised near totally and confirmed to be a schwannoma on histopathological examination. The tumour recurred twice after that and was re operated both times. Another 57 years old lady presented with weakness of both lower limbs and a history of being operated in the past for D9-D10 intramedullary lesion. She was re-operated with total removal of the lesion confirmed to be schwannoma on histopathological examination. Intramedullary schwannoma may recur after resection.

摘要

发生于脊髓内的神经鞘瘤较为罕见,因为施万细胞通常存在于神经根中,而不是脊髓中。迄今为止,英文文献中大约报道了 60 例无神经纤维瘤病的脊髓内神经鞘瘤患者,其中只有 8 例为儿童。我们描述了 2 例胸髓内神经鞘瘤患者,他们在初次切除后复发。一名 10 岁男孩因双下肢无力就诊。磁共振成像显示 D10 至 D12 脊髓内病变,该病变被近全切除,并在组织病理学检查中证实为神经鞘瘤。此后肿瘤复发了 2 次,并进行了 2 次手术。另一位 57 岁女性因双下肢无力就诊,既往曾因 D9-D10 脊髓内病变接受过手术治疗。该患者接受了肿瘤全切除手术,组织病理学检查证实为神经鞘瘤。脊髓内神经鞘瘤切除后可能会复发。

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