纤维肌痛症的诊断时间及初级保健中与延迟诊断相关的因素。

Time to diagnosis of fibromyalgia and factors associated with delayed diagnosis in primary care.

机构信息

Department of Medicine 'B', Sheba Medical Center, Tel-Hashomer, Israel.

Department of Medicine 'B', Sheba Medical Center, Tel-Hashomer, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Best Pract Res Clin Rheumatol. 2018 Aug;32(4):489-499. doi: 10.1016/j.berh.2019.01.019. Epub 2019 Mar 4.

Abstract

Fibromyalgia is a complex disorder, and its diagnosis often comprises a challenge for physicians. We aimed to assess the time from the appearance of early symptoms to the definite diagnosis of fibromyalgia and to delineate patient and physician factors associated with this delay. The database of a large healthcare services provider was searched for all fibromyalgia patients (age 21 years or more) diagnosed during 2008-2011. Patients with a diagnosis confirmed by a physician with a relevant specialization were compared with age- and sex-matched nonfibromyalgia controls to retrospectively identify an initial complaint pattern characteristic of fibromyalgia. The time from initial complaints to fibromyalgia diagnosis, as well as the fraction of time while the patient was treated continuously by the same primary physician as at time of diagnosis, was assessed among all eligible fibromyalgia patients. An initial complaint pattern was identified in 67.9% of 2,055 patients with confirmed fibromyalgia vs. 27.6% of 9,172 controls. Among 2,369 (69.0%) of all 3,434 eligible patients with fibromyalgia, mean (SD) total time to diagnosis was 6.42 (3.57) years and mean (SD) time while treated by the same primary physician as at diagnosis was 3.75 (3.26) years. Comorbidity, younger patient, and older physician age were associated with longer time to diagnosis. By analysis of "real-world" data, fibromyalgia remains a complex and elusive diagnosis, taking years to be properly diagnosed. There is a need to increase the awareness of this syndrome among physicians, especially of older age.

摘要

纤维肌痛是一种复杂的疾病,其诊断常常对医生构成挑战。我们旨在评估从早期症状出现到纤维肌痛明确诊断的时间,并描述与这种延迟相关的患者和医生因素。搜索了一家大型医疗服务提供商的数据库,以寻找所有在 2008-2011 年期间被诊断为纤维肌痛的患者(年龄 21 岁或以上)。将有相关专业医生诊断确认的患者与年龄和性别匹配的非纤维肌痛对照组进行比较,以回顾性地确定纤维肌痛的初始投诉模式特征。评估了所有符合条件的纤维肌痛患者中,从最初的投诉到纤维肌痛诊断的时间,以及患者在诊断时与同一初级保健医生持续治疗的时间比例。在 2055 名确诊纤维肌痛患者中,有 67.9%的患者出现了初始投诉模式,而在 9172 名对照组患者中,这一比例为 27.6%。在所有 3434 名符合条件的纤维肌痛患者中,有 2369 名(69.0%)患者的平均(SD)总诊断时间为 6.42(3.57)年,平均(SD)与诊断时相同的初级保健医生治疗时间为 3.75(3.26)年。合并症、患者年龄较小和医生年龄较大与诊断时间延长有关。通过对“真实世界”数据的分析,纤维肌痛仍然是一种复杂且难以捉摸的诊断,需要数年时间才能得到正确诊断。需要提高医生对这种综合征的认识,尤其是对老年医生的认识。

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