Lal Pawan, Bains Lovenish, Sawant Gaurish, Saini Rahul, Mandal Shramana
1Department of Surgery, Maulana Azad Medical College, New Delhi, India.
2Department of Pathology, Maulana Azad Medical College, New Delhi, India.
Trop Med Health. 2019 Jun 13;47:37. doi: 10.1186/s41182-019-0164-7. eCollection 2019.
Filarial infections are common in most tropical and subtropical regions of the world. Lymphatic filariasis is caused by either , , or Extralymphatic filariasis presenting as a primary retroperitoneal mass is very rare despite filariasis being endemic in many regions of India. On review of literature, only a few isolated case reports have been described.
We report a case of a huge retroperitoneal cystic mass in a 46-year-old patient who presented with a long-standing, painless progressive abdominal swelling. On examination, there was a large, non-tender, firm swelling of size around 20 × 15 cm occupying the left upper and lower quadrant. The computed tomography of the abdomen was suggestive of thin-walled hypodense cyst of size 25.7 × 15 × 14.3 cm. Laboratory investigations and cyst aspirate were inconclusive for a definite diagnosis. On exploration, a 3-kg cystic mass was removed. The diagnosis of filarial origin was confirmed by the demonstration of microfilaria in the cyst wall and immunochromatographic test (ICT) which was positive.
Retroperitoneal lymphatic cyst of filarial origin is very unusual and requires a high index of suspicion if the patient is an inhabitant of an endemic area. The clinical dilemma cannot be resolved with imaging modalities alone, unless a disease-specific manifestation is there. The retroperitoneal cysts often pose a challenge in their diagnosis and management. Small cysts might respond to medical management, whereas large symptomatic cysts will require excision for the final diagnosis and treatment.
丝虫感染在世界上大多数热带和亚热带地区都很常见。淋巴丝虫病由班氏丝虫、马来丝虫或帝汶丝虫引起。尽管丝虫病在印度许多地区流行,但表现为原发性腹膜后肿块的淋巴外丝虫病非常罕见。经文献检索,仅有少数孤立的病例报告。
我们报告一例46岁患者,患有巨大的腹膜后囊性肿块,表现为长期存在的无痛性进行性腹部肿胀。检查发现,左上下象限有一个大小约20×15厘米的巨大、无压痛、质地坚硬的肿块。腹部计算机断层扫描显示为一个大小为25.7×15×14.3厘米的薄壁低密度囊肿。实验室检查和囊肿抽吸物检查均无法明确诊断。手术探查时,切除了一个3千克的囊性肿块。通过在囊肿壁上发现微丝蚴以及免疫层析试验(ICT)呈阳性,确诊为丝虫起源。
丝虫起源的腹膜后淋巴囊肿非常罕见,如果患者是流行地区的居民,则需要高度怀疑。仅靠影像学检查无法解决临床难题,除非有疾病特异性表现。腹膜后囊肿的诊断和治疗往往具有挑战性。小囊肿可能对药物治疗有反应,而大的有症状囊肿则需要切除以进行最终诊断和治疗。