Hsieh Sun-Wung, Hsiao Shih-Fen, Liaw Lih-Jiun, Huang Ling-Chun, Yang Yuan-Han
Department of Neurology, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University.
Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung Medical University.
Medicine (Baltimore). 2019 Jul;98(29):e16506. doi: 10.1097/MD.0000000000016506.
This study investigated the effects of multiple training modalities (MTM) on senior fitness and neuropsychiatric function in the elderly with subjective memory complaints (SMC).
This study was conducted in 24 elderly subjects with Clinical Dementia Rating (CDR) score of 0 and instrument of ascertainment of dementia 8 (AD8) score of <2. The participants were classified into SMC (n = 7) and non-SMC (n = 17).All were assigned to receive multiple training modalities (1 hour for each training: physical fitness activities, calligraphy or drawing, and meditation) twice a week over a 16-week period.A series of senior fitness test, and neuropsychiatric tests, namely the Traditional Chinese version Mini-Mental Status Examination (MMSE), Cognitive Assessment Screening Instrument (CASI), and the Center for Epidemiologic Studies Depression Scale (CESD), were conducted before and after the intervention. We compared the differences of pre/posttest-MTM and SMC/non-SMC in senior fitness and the neuropsychological tests.
There was no significant difference between SMC and non-SMC groups in demographic characteristics. MTM showed significant improvement in senior fitness and CESD, but not in CASI and MMSE. Significant change in recent memory subscale of CASI was only observed in SMC group, whereas improvement of partial senior fitness and CESD were observed in both groups.
MTM had effects in enhancing senior fitness and improving depressive syndromes in the elderly. MTM contributed to greater improvement in recent memory function in the SMC group than in the non-SMC group.
本研究调查了多种训练方式(MTM)对有主观记忆障碍(SMC)的老年人的身体机能和神经精神功能的影响。
本研究纳入了24名临床痴呆评定量表(CDR)评分为0且痴呆筛查量表8(AD8)评分<2的老年人。参与者被分为SMC组(n = 7)和非SMC组(n = 17)。所有参与者均被安排接受多种训练方式(每次训练1小时:健身活动、书法或绘画以及冥想),每周两次,为期16周。在干预前后进行了一系列身体机能测试和神经精神测试,即中文版简易精神状态检查表(MMSE)、认知评估筛查工具(CASI)以及流行病学研究中心抑郁量表(CESD)。我们比较了MTM前后测试以及SMC/非SMC组在身体机能和神经心理测试方面的差异。
SMC组和非SMC组在人口统计学特征方面无显著差异。MTM在身体机能和CESD方面显示出显著改善,但在CASI和MMSE方面未显示出改善。仅在SMC组中观察到CASI近期记忆子量表有显著变化,而两组在部分身体机能和CESD方面均有改善。
MTM对增强老年人的身体机能和改善抑郁综合征有效果。MTM对SMC组近期记忆功能的改善作用大于非SMC组。