发自颧骨的骨化性纤维瘤:一例报告。
Ossifying fibroma arising from the zygomatic arch: A case report.
机构信息
Oral and Maxillofacial Surgery, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549 Japan; Division of Dentistry and Oral Surgery, Hitachi, Ltd. Hitachinaka General Hospital, 20-1, Ishikawa-cho, Hitachinaka-shi, Ibaraki-ken, 312-0057 Japan.
Oral and Maxillofacial Surgery, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549 Japan.
出版信息
J Stomatol Oral Maxillofac Surg. 2020 Jun;121(3):288-291. doi: 10.1016/j.jormas.2019.08.004. Epub 2019 Aug 30.
INTRODUCTION
Ossifying fibroma (OF) is a rare type of tumor characterized by fibrous tissue proliferation with cementum- or bone-like hard tissue formation. Since its first report by Montgomery in 1927, several cases of OF have been reported; however, no cases of OF arising from the zygomatic arch have been reported. Herein, we report a case of OF arising from the zygomatic arch.
CLINICAL CASE SUMMARY
A 70-year-old female visited our department in February 2017 because of a gradually growing osseous protrusion in the right zygomatic region, which she was aware of since the previous 6 months. A 3.3cm×3.2-cm area of swelling was observed in the region. Computed tomography confirmed the presence of a granulated lesion on the surface of the right zygomatic arch. Accordingly, benign bone tumor was diagnosed, and tumor resection was subsequently performed. Histopathological analysis revealed irregularly arranged bone trabeculae, an increased number of fibroblasts, and collagen fibers between the bone trabeculae; accordingly, OF was diagnosed. No clinical or radiographic evidence of recurrence was observed during the 1.5-year follow-up period.
DISCUSSION
A granulated lesion was present on the surface of the right zygomatic arch, and the boundary between the lesion and surrounding bone was clear. Resection of the lesion from the zygomatic arch was relatively easy. Thus, OF was diagnosed. If OF is suspected, a risk of recurrence persists; therefore, shaving the area including the bones surrounding the lesion may be necessary. Although detailed causes of OF and osteoma remain unknown, past trauma has been indicated as a common etiology. However, compared with the frequency of fractures in the zygomatic arch, the frequency of OF and osteoma is rare; thus, the etiology of OF and osteoma remains to be fully elucidated.
简介
骨化性纤维瘤(OF)是一种罕见的肿瘤类型,其特征为纤维组织增生,并伴有牙骨质或骨样硬组织形成。自 1927 年 Montgomery 首次报道以来,已经有几例 OF 的病例报告;然而,尚无发生于颧骨的 OF 病例报告。在此,我们报告一例发生于颧骨的 OF。
临床病例总结
一位 70 岁女性因右侧颧骨区域逐渐增大的骨性突起于 2017 年 2 月就诊于我科,她在 6 个月前就已经注意到该突起。该区域观察到一个 3.3cm×3.2cm 的肿胀区域。计算机断层扫描(CT)确认右侧颧骨表面存在一个肉芽病变。因此,诊断为良性骨肿瘤,并随后进行了肿瘤切除术。组织病理学分析显示骨小梁排列不规则,骨小梁之间有较多的成纤维细胞和胶原纤维;因此,诊断为 OF。在 1.5 年的随访期间,未观察到临床或影像学复发的证据。
讨论
右侧颧骨表面存在一个肉芽病变,病变与周围骨骼之间的边界清晰。从颧骨切除病变相对容易。因此,诊断为 OF。如果怀疑 OF,则存在复发的风险;因此,可能需要切除包括病变周围骨骼在内的区域。尽管 OF 和骨瘤的确切病因尚不清楚,但既往外伤被认为是一种常见病因。然而,与颧骨骨折的频率相比,OF 和骨瘤的频率较低;因此,OF 和骨瘤的病因仍有待充分阐明。