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扳机指皮质类固醇注射联合或不联合局部麻醉:一项随机、双盲对照试验。

Trigger Finger Corticosteroid Injection With and Without Local Anesthetic: A Randomized, Double-Blind Controlled Trial.

机构信息

Vanderbilt University School of Medicine, Nashville, TN, USA.

Vanderbilt University Medical Center, Nashville, TN, USA.

出版信息

Hand (N Y). 2021 Sep;16(5):619-623. doi: 10.1177/1558944719884663. Epub 2019 Nov 5.

Abstract

The first-line treatment for trigger finger is a corticosteroid injection. Although the injectable solution is often prepared with a local anesthetic, we hypothesize that patients receiving an injection with anesthetic will experience more pain at the time of injection. C Patients with trigger finger were prospectively randomized into 2 cohorts to receive triamcinolone (1 mL, 40 mg) plus 1% lidocaine with epinephrine (1 mL) or triamcinolone (1 mL, 40 mg) plus normal saline (1 mL, placebo). Both patient and surgeon were blinded to the treatment arm. The primary outcome was pain measured using a (VAS) immediately following the injection. Seventy-three patients with a total of 110 trigger fingers were enrolled (57 lidocaine with epinephrine and 53 placebo). Immediate postinjection pain scores were significantly higher for injections containing lidocaine with epinephrine compared with placebo (VAS 3.5 vs 2.0). In the treatment of trigger finger, corticosteroid injections are effective and have relatively little associated pain. This study shows there is more injection-associated pain when lidocaine with epinephrine is included with the corticosteroid. Therefore, surgeons looking to decrease injection pain should exclude the anesthetic, but they should discuss the trade-off of foregoing short-term anesthesia with patients. Using only a single drug (ie, corticosteroid alone) is not only less painful but is also more simple, efficient, and safe; this has therefore become our preferred treatment method.

摘要

扳机指的一线治疗方法是皮质类固醇注射。虽然注射溶液通常与局部麻醉剂混合制备,但我们假设接受含麻醉剂注射的患者在注射时会感到更多疼痛。

扳机指患者前瞻性随机分为 2 组,接受曲安奈德(1 毫升,40 毫克)加 1%利多卡因加肾上腺素(1 毫升)或曲安奈德(1 毫升,40 毫克)加生理盐水(1 毫升,安慰剂)。患者和外科医生均对治疗臂不知情。主要结局是注射后立即使用视觉模拟评分(VAS)测量疼痛。

共有 73 名患者的 110 个扳机指纳入研究(57 例含肾上腺素的利多卡因,53 例安慰剂)。含肾上腺素的利多卡因注射后的即刻疼痛评分明显高于安慰剂(VAS3.5 比 2.0)。

在扳机指的治疗中,皮质类固醇注射有效,且相关疼痛相对较小。本研究表明,皮质类固醇中加入肾上腺素和利多卡因会增加注射相关疼痛。因此,希望减少注射疼痛的外科医生应排除麻醉剂,但应与患者讨论放弃短期麻醉的权衡利弊。仅使用一种药物(即皮质类固醇单独使用)不仅疼痛更小,而且更简单、更有效且更安全;因此,这已成为我们首选的治疗方法。

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