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渐进性张力缝线不引流在减少腹部整形术后血清肿发生率中的效果:系统评价和荟萃分析。

Efficacy of Progressive Tension Sutures without Drains in Reducing Seroma Rates of Abdominoplasty: A Systematic Review and Meta-Analysis.

机构信息

Beijing Medical Aesthetic Plastic Clinic, Chaoyang, Beijing, China.

Beijing Medical Aesthetic Plastic Hospital, Chaoyang, Beijing, China.

出版信息

Aesthetic Plast Surg. 2021 Apr;45(2):581-588. doi: 10.1007/s00266-020-01913-w. Epub 2020 Aug 27.

Abstract

BACKGROUND

Abdominoplasty using progressive tension sutures (PTS) without drains has been reported to lower seroma risk. However, evidence regarding the reproducibility of PTS drainless abdominoplasty in lowering seroma risk is inconsistent and limited to a few studies.

OBJECTIVES

The purpose of this review and meta-analysis was to assess the efficacy of PTS without drains in reducing seroma rates associated with abdominoplasty.

METHODS

PubMed, EMBASE, and Cochrane databases were searched with no restrictions for randomized controlled trials (RCTs) and observational studies in which the number of patients who experienced postoperative seroma was indicated. The keywords included ''progressive tension sutures,'' ''quilting sutures,'' "drain," and "abdominoplasty.'' Review Manager software (RevMan, version 5.3) was utilized to compute the pooled effect estimate using a random-effects Mantel-Haenszel model. The outcomes were expressed as odds ratios (OR) and 95% confidence intervals (CI). Subgroup analysis was conducted based on whether abdominoplasty was combined with liposuction.

RESULTS

Five studies were included (one RCT and four retrospective studies) involving a total of 1255 adult patients. Patients who underwent abdominoplasty using PTS without drains experienced a significantly lower rate of postoperative seroma compared to those with drains (D) only (OR, 0.36; 95% CI, 0.19-0.70; P = 0.002; I = 9%). There was no significant difference in postoperative seroma rates between the PTS and PTS + D groups (OR, 1.03; 95% CI, 0.30-3.54; P = 0.96; I = 0%). The data analysis for the subgroup that included liposuction showed that compared with the use of drain only, PTS were associated with a significantly reduced number of seromas (OR, 0.24; 95% CI, 0.11-0.49; P = 0.0001; I = 0%).

CONCLUSION

Abdominoplasty using PTS without drain and combined with liposuction was effective in reducing seroma rates. Additional RCTs with larger sample sizes and better comparability are needed to confirm the safety and effectiveness of the drainless abdominoplasty technique using progressive tension sutures.

LEVEL OF EVIDENCE III

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

摘要

背景

使用渐进式张力缝线(PTS)而非引流管进行腹部整形术已被报道可降低血清肿风险。然而,关于 PTS 无引流管腹部整形术降低血清肿风险的可重复性的证据并不一致,并且仅限于少数研究。

目的

本综述和荟萃分析的目的是评估 PTS 无引流管在降低与腹部整形术相关的血清肿发生率方面的疗效。

方法

检索了 PubMed、EMBASE 和 Cochrane 数据库,对随机对照试验(RCT)和观察性研究进行了无限制检索,其中表明了术后发生血清肿的患者数量。关键词包括“渐进式张力缝线”、“绗缝缝线”、“引流管”和“腹部整形术”。使用 Review Manager 软件(RevMan,版本 5.3)使用随机效应 Mantel-Haenszel 模型计算汇总效应估计值。结果表示为比值比(OR)和 95%置信区间(CI)。根据是否结合抽脂术进行了亚组分析。

结果

共纳入了 5 项研究(1 项 RCT 和 4 项回顾性研究),共纳入了 1255 例成年患者。与仅使用引流管(D)的患者相比,使用 PTS 无引流管的患者术后血清肿发生率显著降低(OR,0.36;95%CI,0.19-0.70;P=0.002;I²=9%)。PTS 组与 PTS+D 组的术后血清肿发生率无显著差异(OR,1.03;95%CI,0.30-3.54;P=0.96;I²=0%)。纳入抽脂术的亚组数据分析显示,与仅使用引流管相比,PTS 与血清肿数量显著减少相关(OR,0.24;95%CI,0.11-0.49;P=0.0001;I²=0%)。

结论

使用 PTS 无引流管联合抽脂术的腹部整形术可有效降低血清肿发生率。需要更大样本量和更好可比性的 RCT 来证实 PTS 无引流管腹部整形术的安全性和有效性。

证据水平 III:本杂志要求作者为每篇文章分配一个证据水平。有关这些循证医学评级的完整描述,请参阅目录或在线作者指南 www.springer.com/00266

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