保留止点腘绳肌腱移植物前交叉韧带整体成熟度 5 年进展:基于磁共振成像评估的前瞻性随机对照研究。
Maturity Progression of the Entire Anterior Cruciate Ligament Graft of Insertion-Preserved Hamstring Tendons by 5 Years: A Prospective Randomized Controlled Study Based on Magnetic Resonance Imaging Evaluation.
机构信息
Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Department of Biology, Boston University, Boston, Massachusetts, USA.
出版信息
Am J Sports Med. 2020 Oct;48(12):2970-2977. doi: 10.1177/0363546520951507. Epub 2020 Sep 10.
BACKGROUND
It has been reported that insertion-preserved hamstring tendon autografts (IP-HT) have better maturity than free hamstring tendon autografts (FHT) at 2 years after anterior cruciate ligament reconstruction (ACLR); however, whether insertion preservation improves the maturity of the entire autograft and clinical outcomes at 5 years after ACLR is still unclear.
PURPOSE
To investigate the clinical outcomes and maturity of different segments using insertion-preserved and free hamstring tendon autografts up to 5 years after ACLR.
STUDY DESIGN
Randomized controlled trial; Level of evidence, 2.
METHODS
45 patients who underwent isolated ACLR with hamstring tendon autografts were enrolled and randomized into 2 groups. The study group had ACLR with IP-HT, whereas the control group had ACLR with FHT. The International Knee Documentation Committee and Tegner scores, Lysholm activity score, and KT-1000 arthrometer measurements were evaluated preoperatively and at 6, 12, 24, and 60 months postoperatively. Three-dimensional-reconstruction MRI examinations were performed at 6, 12, 24, and 60 months to evaluate the signal/noise quotient (SNQ) values of femoral tunnel graft, intra-articular graft, and tibial tunnel graft.
RESULTS
At 60 months, the SNQ values of the intra-articular and tunnel sections for the grafts in both groups showed no difference; the clinical outcomes were improved compared with before surgery ( < .001) and were similar in both groups. In the early stage, all graft segments in the IP-HT group had lower SNQ values than those of the FHT group. At 6 months, the entire graft in the FHT group and the femoral tunnel section in the IP-HT group had the maximum SNQ values, whereas the femoral tunnel graft had the highest SNQ value compared with intra-articular and tibial tunnel graft in each group. SNQ values of the intra-articular and tibial tunnel graft in the IP-HT group had no significant change within 60 months.
CONCLUSION
All patients had similar clinical outcomes and graft maturity at 60 months postoperatively. The SNQ values and progressions varied at different graft sites and were highest for the femoral tunnel graft. All significantly changing SNQ values reached the maximum value at 6 months. Compared with FHT autograft, the graft maturity of IP-HT autograft recovered earlier and appeared more stable within the 60-month follow-up; however, no significant association was found between graft maturity and clinical scores.
背景
据报道,在前交叉韧带重建(ACLR)后 2 年,保留止点的腘绳肌腱自体移植物(IP-HT)的成熟度优于游离腘绳肌腱自体移植物(FHT);然而,保留止点是否能提高 ACLR 后 5 年时整个自体移植物的成熟度和临床结果仍不清楚。
目的
研究保留止点和游离腘绳肌腱自体移植物在前交叉韧带重建后 5 年内不同节段的临床结果和成熟度。
研究设计
随机对照试验;证据水平,2 级。
方法
纳入 45 例接受腘绳肌腱自体移植物重建 ACL 的患者,并随机分为 2 组。研究组行 ACLR 联合 IP-HT,对照组行 ACLR 联合 FHT。术前及术后 6、12、24 和 60 个月,采用国际膝关节文献委员会(IKDC)和 Tegner 评分、Lysholm 活动评分和 KT-1000 关节测量仪进行评估。术后 6、12、24 和 60 个月,行三维重建 MRI 检查,评估股骨隧道移植物、关节内移植物和胫骨隧道移植物的信噪比(SNQ)值。
结果
60 个月时,两组关节内和隧道段移植物的 SNQ 值无差异;与术前相比,临床结果均有所改善(<.001),且两组间相似。在早期,IP-HT 组所有移植物节段的 SNQ 值均低于 FHT 组。术后 6 个月时,FHT 组的整个移植物和 IP-HT 组的股骨隧道段的 SNQ 值最大,而每组的股骨隧道移植物的 SNQ 值均高于关节内和胫骨隧道移植物。IP-HT 组关节内和胫骨隧道移植物的 SNQ 值在 60 个月内无明显变化。
结论
术后 60 个月时,所有患者的临床结果和移植物成熟度相似。不同移植物部位的 SNQ 值和进展情况不同,股骨隧道移植物的 SNQ 值最高。所有显著变化的 SNQ 值均在 6 个月时达到最大值。与 FHT 自体移植物相比,IP-HT 自体移植物的成熟度恢复得更早,在 60 个月的随访中更为稳定;然而,移植物成熟度与临床评分之间无明显相关性。