冠状病毒和 COVID-19 的研究与专利:综述。
Research and Patents on Coronavirus and COVID-19: A Review.
机构信息
Materials Science Institute of Madrid, ICMM-CSIC, c/Sor Juana Ines de la Cruz 3, 28049, Madrid, Spain.
Centre National de la Recherche Scientifique, CNRS, CEMHTI, (UPR 3079), Universite d'Orleans, 45071 Orleans, France.
出版信息
Recent Pat Nanotechnol. 2020;14(4):328-350. doi: 10.2174/1872210514666201021145735.
BACKGROUND
COVID-19 pandemic is a global problem that requires the point of view of basic sciences and medicine as well as social, economics and politics disciplines. Viral particles of coronaviruses including SARS-CoV-2 as well as other enveloped viruses like influenza virus could be considered as an approximation to functional core-shell nanoparticles and therefore, their study enters the realm of nanotechnology. In this context, nanotechnology can contribute to alleviate some of the current challenges posed by COVID-19 pandemic.
METHODS
The present analysis contributed to diverse sources of general information, databases on scientific literature and patents to produce a review affording information on relevant areas where as nanotechnology has offered response to coronavirus challenges in the past and may be relevant now, and has offered an update of the current information on SARS-CoV-2 and COVID-19 issues.
RESULTS
This review contribution includes specific information including: 1) An introduction to current research on nanotechnology and related recent patents for COVID-19 responses; 2) Analysis of nonimmunogenic and immunogenic prophylaxis of COVID-19 using Nanotechnology; 3) Tools devoted to detection & diagnosis of coronaviruses and COVID-19: the role of Nanotechnology; and 4) A compilation on the research and patents on nanotechnology dealing with therapeutics & treatments of COVID-19.
CONCLUSION
Among the increasing literature on COVID-19, there are few works analyzing the relevance of Nanotechnology, and giving an analysis on patents dealing with coronaviruses that may provide useful information on the area. This review offers a general view of the current research investigation and recent patents dealing with aspects of immunogenic and non-immunogenic prophylaxis, detection and diagnosis as well as therapeutics and treatments.
背景
COVID-19 大流行是一个全球性问题,需要基础科学和医学以及社会、经济和政治学科的观点。包括 SARS-CoV-2 在内的冠状病毒的病毒颗粒以及流感病毒等其他包膜病毒,可以被视为功能核壳纳米粒子的近似物,因此,它们的研究进入了纳米技术领域。在这种情况下,纳米技术可以有助于缓解 COVID-19 大流行带来的一些当前挑战。
方法
本分析有助于从一般信息的多种来源、科学文献数据库和专利中获取信息,以提供有关纳米技术过去应对冠状病毒挑战的相关领域的信息,现在可能相关的信息,并提供有关 SARS-CoV-2 和 COVID-19 问题的最新信息。
结果
本综述贡献包括具体信息,包括:1)介绍当前纳米技术研究和相关的 COVID-19 应对专利;2)使用纳米技术分析 COVID-19 的非免疫和免疫预防;3)用于检测和诊断冠状病毒和 COVID-19 的工具:纳米技术的作用;4)关于处理 COVID-19 治疗的纳米技术研究和专利的汇编。
结论
在 COVID-19 的不断增加的文献中,很少有作品分析纳米技术的相关性,并对涉及冠状病毒的专利进行分析,这可能为该领域提供有用的信息。本综述提供了对当前研究调查和最近处理免疫和非免疫预防、检测和诊断以及治疗的专利的一般看法。