Rehabilitation Medicine, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
J Rehabil Med. 2021 Mar 9;53(3):jrm00162. doi: 10.2340/16501977-2807.
To explore the effects of transcranial direct current stimulation combined with cognitive training on executive function and activities of daily living performance among stroke patients.
A total of 50 subjects were enrolled and randomly allocated into 2 groups of 25 each. The real-transcranial direct current stimulation group was simultaneously subjected to transcranial direct current stimulation and cognitive training, while the sham-transcranial direct current stimulation group was simultaneously subjected to sham transcranial direct current stimulation and cognitive training. At baseline, and after treatment, each subject was assessed with the Wisconsin Card Sorting Test (WCST), Stroop Color-Word Test (SCWT), Digital Symbol Test (DST), Mini-mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA) and Activities of Daily Living Scale (ADLs).
After treatment, the gains in most indices of WCST, SCWT, DST, MMSE, MoCA and ADLs in the real-transcranial direct current stimulation group were significantly higher than those in the sham-transcranial direct current stimulation group (p<0.05). Nonetheless, no significant differences were noted in the gains in SCWT (including only Part A time and error, and Part B time) and activities of daily living (including only basic activities of daily living) between the 2 groups (p>>0.05).
Transcranial direct current stimulation combined with cognitive training was found to significantly enhance executive function and instrumental activities of daily living performance among stroke patients.
探讨经颅直流电刺激联合认知训练对脑卒中患者执行功能和日常生活活动能力的影响。
共纳入 50 例患者，随机分为真经颅直流电刺激组和假经颅直流电刺激组，每组 25 例。真经颅直流电刺激组同时进行经颅直流电刺激和认知训练，假经颅直流电刺激组同时进行假经颅直流电刺激和认知训练。在基线时和治疗后，所有患者均接受威斯康星卡片分类测试（WCST）、斯特鲁普色词测验（SCWT）、数字符号测试（DST）、简易精神状态检查（MMSE）、蒙特利尔认知评估（MoCA）和日常生活活动量表（ADLs）评估。
治疗后，真经颅直流电刺激组 WCST、SCWT、DST、MMSE、MoCA 和 ADL 各项指标的改善均明显优于假经颅直流电刺激组（p<0.05）。但 2 组间 SCWT（仅包括 A 部分时间和错误，以及 B 部分时间）和日常生活活动（仅包括基本日常生活活动）的改善无显著差异（p>>0.05）。
经颅直流电刺激联合认知训练可显著提高脑卒中患者的执行功能和工具性日常生活活动能力。
