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围产期妇女对 COVID-19 疫苗的犹豫:一项横断面调查。

COVID-19 vaccine hesitancy in perinatal women: a cross sectional survey.

机构信息

Department of Obstetrics and Gynaecology, Sidra Medicine, Doha, Qatar.

Weill Cornell Medicine, Doha, Qatar.

出版信息

J Perinat Med. 2021 Apr 28;49(6):678-685. doi: 10.1515/jpm-2021-0069. Print 2021 Jul 27.

Abstract

OBJECTIVES

To explore attitudes to COVID-19 vaccination among perinatal women.

METHODS

A nationwide online, cross-sectional survey was conducted in Qatar from 15th October 2020 to 15th November 2020 with voluntary participation open to all adult residents. Of the respondents, the population group for this study comprised the 341 pregnant and breastfeeding participants. The survey utilized a composite questionnaire incorporating a validated instrument to measure vaccine attitudes. The responses were recorded and analysed with statistical analysis being performed with SPSS software. Outcome measures included intentions towards vaccination and potential factors influencing vaccine hesitancy (contextual factors, vaccine specific concerns and group/individual influences).

RESULTS

Perinatal women exhibited a vaccine hesitancy rate of 25% towards COVID-19 immunisation. The main concerns of the group were of infection risks and main factor determining vaccine hesitancy was of vaccine specific safety concerns. Previous vaccine "acceptors" showed vaccine hesitancy to COVID-19 immunisation. A third of the group cited non availability of the vaccine as a concern.

CONCLUSIONS

COVID-19 vaccine trials amongst pregnant and lactating women have lagged behind those for general populations and this has compounded concerns around safety in this special group. Perinatal women constitute a vulnerable group and play an important role in vaccination of wider family members. This study highlights the need for trials and data for COVID-19 vaccine in this group to be able to achieve appreciable numbers needed for herd immunity and ultimately control of the pandemic.

摘要

目的

探讨围产期妇女对 COVID-19 疫苗接种的态度。

方法

2020 年 10 月 15 日至 11 月 15 日,在卡塔尔进行了一项全国性的在线横断面调查,所有成年居民均可自愿参与。在应答者中,本研究的人群组由 341 名孕妇和哺乳期参与者组成。该调查采用了一个综合问卷,其中包含了一个经过验证的测量疫苗态度的工具。记录了应答者的回答并进行了分析,统计分析使用了 SPSS 软件。主要结局指标包括接种疫苗的意向以及可能影响疫苗犹豫的因素(背景因素、疫苗特定关注问题和群体/个体影响)。

结果

围产期妇女对 COVID-19 免疫接种的疫苗犹豫率为 25%。该人群的主要关注点是感染风险,决定疫苗犹豫的主要因素是疫苗特定的安全性问题。之前的疫苗“接受者”对 COVID-19 免疫接种也表现出了疫苗犹豫。该组中有三分之一的人提到了疫苗的不可获得性是一个关注点。

结论

在孕妇和哺乳期妇女中进行 COVID-19 疫苗试验滞后于普通人群,这加剧了人们对这一特殊群体安全性的担忧。围产期妇女是一个脆弱的群体,在为更广泛的家庭成员接种疫苗方面发挥着重要作用。本研究强调了在这一人群中进行 COVID-19 疫苗试验和数据的必要性,以获得实现群体免疫和最终控制大流行所需的可观数量。

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