围手术期放射治疗对下咽重建中狭窄和瘘管形成的影响：一项荟萃分析。

Effects of perioperative radiation treatment on stricture and fistula formation in hypopharyngeal reconstruction: a meta-analysis.

作者信息

Shin Jin Yong, Lee Sun-Young, Roh Si-Gyun, Lee Nae-Ho

机构信息

Department of Plastic and Reconstructive Surgery, Jeonbuk National University Medical School, Jeonju, Korea.

Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea.

出版信息

Arch Craniofac Surg. 2021 Apr;22(2):71-77. doi: 10.7181/acfs.2021.00080. Epub 2021 Apr 20.

DOI:10.7181/acfs.2021.00080

PMID:33957731

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8107459/

Abstract

Hypopharyngeal reconstruction is a surgically challenging procedure, and postoperative management is important due to a high rate of complications following surgery. In particular, stricture and fistula formation is the most common long-term postoperative complication. Through systematic review and meta-analysis of 21 studies, a significant radiation effect of stricture and fistula formation was found in patients who underwent hypopharyngeal reconstruction. The perioperative radiation must be seen as a critical factor for stricture and fistula formation in hypopharyngeal reconstruction.

摘要

下咽重建是一项具有手术挑战性的操作，由于手术后并发症发生率高，术后管理很重要。特别是，狭窄和瘘管形成是最常见的术后长期并发症。通过对21项研究的系统评价和荟萃分析，发现接受下咽重建的患者中，狭窄和瘘管形成存在显著的放射效应。围手术期放疗必须被视为下咽重建中狭窄和瘘管形成的关键因素。