Servicio de Reumatología, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico.
Facultad de Medicina y Hospital Universitario de la Universidad Autónoma de Monterrey, Nuevo León, Nuevo León, Mexico.
Reumatol Clin (Engl Ed). 2021 Dec;17(10):611-621. doi: 10.1016/j.reumae.2020.12.002. Epub 2021 Jul 23.
Psoriatic arthritis is a chronic systemic inflammatory disease that affects the skin, musculoskeletal structures and other organs and systems compromising functionality, quality of life and reducing the life expectancy of patients. It is a complex disease that requires specialist and timely care and management. The alternatives for treating the manifestations of psoriatic arthritis have increased and the effect of the different agents on specific manifestations has been clarified in recent studies. Therefore, we should incorporate the available evidence to build a strategy for the treatment of these patients. The Mexican College of Rheumatology selected a committee to evaluate these different alternatives and make recommendations.
The study group included 16 rheumatologists and 3 certified dermatologists, selected from different health institutions and regions of the country. An executive committee was formed to coordinate the meetings and a committee of experts selected the literature search criteria, prepared the research questions, rated the quality of the evidence, and produced the recommendations in the different disease domains based on the GRADE methodology.
24 updated recommendations were generated for the treatment of patients with psoriatic arthritis. The recommendations establish the role of the drugs currently available in our country. The importance of adequate disease control is emphasized, individualizing the level of involvement of each patient in each of the six domains potentially affected by the disease. In addition, the sequence in the choice of treatments available for each domain is established, based on their efficacy, safety profile and accessibility.
With this consensus document, it will be possible to improve the care of patients with psoriatic arthritis. The recommendations were generated based on the best available information and in consideration of the Mexican health system.
银屑病关节炎是一种慢性全身性炎症性疾病,影响皮肤、肌肉骨骼结构和其他器官和系统,损害功能、生活质量,并降低患者的预期寿命。它是一种复杂的疾病,需要专业人员及时的护理和管理。治疗银屑病关节炎表现的选择已经增加,并且最近的研究已经阐明了不同药物对特定表现的影响。因此,我们应该整合现有证据,为这些患者制定治疗策略。墨西哥风湿病学会选择了一个委员会来评估这些不同的选择并提出建议。
研究小组包括 16 名风湿病专家和 3 名认证皮肤科医生,他们来自不同的医疗机构和国家的不同地区。成立了一个执行委员会来协调会议,一个专家委员会选择了文献检索标准,准备了研究问题,根据 GRADE 方法对证据质量进行了评分,并根据不同疾病领域生成了建议。
针对银屑病关节炎患者的治疗,生成了 24 项更新的建议。这些建议确立了我们国家目前可用药物的作用。强调了充分控制疾病的重要性,根据每个患者在疾病可能影响的六个领域中的参与程度对其进行个体化。此外,根据每种药物的疗效、安全性和可及性,在每个领域中确定了可用治疗方法的选择顺序。
通过这份共识文件,将有可能改善银屑病关节炎患者的护理。这些建议是基于最佳现有信息,并考虑到墨西哥的卫生系统而制定的。