Department of Family Medicine, Başkent University School of Medicine, Ankara, Turkey.
Department of General Surgery, Başkent University School of Medicine, Ankara, Turkey.
Turk J Gastroenterol. 2021 Sep;32(9):801-807. doi: 10.5152/tjg.2021.21229.
The only treatment in patients developing liver failure is liver transplantation. According to the Ministry of Health, the number of patients waiting for a liver transplantation is 2141, the average waiting period for liver transplantation is approximately 5 years, and 15-18% of these patients lose their life while waiting for transplantation. In these patients, limitations in daily activities and depression-anxiety are commonly found. The aim of this study was to analyze life quality, depression symptoms, and existence of sexual functional disorders of patients waiting for liver transplantation.
A total of 74 patients, who were registered in Başkent University Hospital between 2015 and 2018, were included into the study. Short Form-36, Beck Depression Inventory, and Arizona Sexual Experiences Scale were applied to 56 patients who approved study.
Most of the patients were male (64.3%), and the mean age was 46 (18-64). Short Form-36 scores were low in all patients. The mean Beck Depression Inventory score of patients was found as 18.4 ± 11.3, and they were suffering from moderate depressive symptoms. According to Arizona Sexual Experiences Scale, total mean scores of males was found as 16.3 ± 5.5, and for females, it was 19.5 ± 5.3 with a statistically significant difference (P < .05). It was found that sexual dysfunction mostly had moderate to mild.
Depression and sexual dysfunction are common in patients with chronic liver diseases, and their life qualities deteriorate significantly. It is anticipated that evaluation of these patients in terms of psychological issues and sexual dysfunction will increase their quality of life during the organ waiting period and affect their well-being post-transplant.
在发生肝功能衰竭的患者中,唯一的治疗方法是肝移植。根据卫生部的数据,有 2141 名患者等待肝移植,肝移植的平均等待时间约为 5 年,其中 15-18%的患者在等待移植时失去生命。在这些患者中,常见的是日常活动受限和抑郁焦虑。本研究旨在分析等待肝移植患者的生活质量、抑郁症状和性功能障碍的存在情况。
共有 74 名于 2015 年至 2018 年在巴什肯特大学医院登记的患者纳入本研究。对 56 名同意研究的患者应用简明健康调查问卷(SF-36)、贝克抑郁量表(BDI)和亚利桑那性体验量表(ASEX)进行评估。
大多数患者为男性(64.3%),平均年龄为 46 岁(18-64 岁)。所有患者的 SF-36 评分均较低。患者的平均 BDI 评分为 18.4 ± 11.3,患有中度抑郁症状。根据 ASEX,男性的总平均得分为 16.3 ± 5.5,女性的总平均得分为 19.5 ± 5.3,存在统计学差异(P<.05)。发现性功能障碍主要为中至轻度。
慢性肝病患者中抑郁和性功能障碍很常见,他们的生活质量明显恶化。预计对这些患者进行心理问题和性功能障碍评估将提高他们在器官等待期间的生活质量,并影响他们移植后的幸福感。